DGIdb - VEGFC Gene Record

VEGFC 7424 Druggable GenomeDrug Resistance

Alternate Names:

7424
VASCULAR ENDOTHELIAL GROWTH FACTOR C
VEGFC
Flt4-L
LMPH1D
VRP
601528
12682
ENSG00000150630
OTTHUMG00000160734
PA37304
Flt4 ligand
Vascular endothelial growth factor-related protein
VEGF-C
P49767
T51425
6073

Gene Info:

Gene Biotype	PROTEIN_CODING

(6 More Sources)

Gene Categories: Category Details

TRANSPORTER
GROWTH FACTOR
DRUG RESISTANCE
DRUGGABLE GENOME

Publications:

Maitland ML et al., 2010, Vascular endothelial growth factor pathway., Pharmacogenet Genomics
Harmon CS et al., 2011, Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib., J Transl Med

VGX-100 VEGFC

Interaction Score: 9.47

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
AFLIBERCEPT VEGFC

Interaction Score: 3.79

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20124951

Sources:
PharmGKB
CONBERCEPT VEGFC

Interaction Score: 2.37

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vascular endothelial growth factor C inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
BEVACIZUMAB VEGFC

Interaction Score: 0.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20124951

Sources:
ClearityFoundationClinicalTrial PharmGKB
LENALIDOMIDE VEGFC

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
ClearityFoundationClinicalTrial
SUNITINIB VEGFC

Interaction Score: 0.44

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21787417

Sources:
CIViC

Ensembl: ENSG00000150630
- Version: 101_38
Alternate Names:

VEGFC Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
PharmGKB: VEGFC
- Version: 18-August-2020
Alternate Names:

PA37304 PharmGKB ID

Gene Info:

Publications:

Maitland ML et al., 2010, Vascular endothelial growth factor pathway., Pharmacogenet Genomics
CIViC: VEGFC
- Version: 14-September-2020
Alternate Names:

7424 Entrez Gene ID

6073 CIViC Gene ID

Gene Info:

Publications:

Harmon CS et al., 2011, Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib., J Transl Med
ChemblInteractions: VEGFC
- Version: chembl_23
Alternate Names:

VEGFC GENE_SYMBOL

Vascular endothelial growth factor C UNIPROT

Flt4 ligand UNIPROT

Gene Info:

Publications:
HingoraniCasas: ENSG00000150630
- Version: 31-May-2017
Alternate Names:

ENSG00000150630 Gene Symbol

VEGFC Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
HumanProteinAtlas: VEGFC
- Version: 19.3
Alternate Names:

ENSG00000150630 Ensembl Gene ID

VRP Human Protein Atlas Gene Synonym

Vascular endothelial growth factor C Human Protein Atlas Gene Description

Gene Info:

Gene Categories:

TRANSPORTER

Publications:
TTD: Vascular endothelial growth factor C
- Version: 2020.06.01
Alternate Names:

VEGFC TTD Gene Abbreviation

T51425 TTD Target ID

Gene Info:

Publications:
ClearityFoundationClinicalTrial: VEGFC
- Version: 15-June-2013
Alternate Names:

Gene Info:

Publications:
MyCancerGenomeClinicalTrial: VEGFC
- Version: 30-February-2014
Alternate Names:

Gene Info:

Publications:
GO: VEGFC
- Version: 05-September-2020
Alternate Names:

Gene Info:

Gene Categories:

GROWTH FACTOR, DRUG RESISTANCE

Publications:

Mechanism of Interaction	Vascular endothelial growth factor C inhibitor
Direct Interaction	yes

VEGFC	GENE_SYMBOL
Vascular endothelial growth factor C	UNIPROT
Flt4 ligand	UNIPROT

ENSG00000150630	Ensembl Gene ID
VRP	Human Protein Atlas Gene Synonym
Vascular endothelial growth factor C	Human Protein Atlas Gene Description

VEGFC	TTD Gene Abbreviation
T51425	TTD Target ID

VEGFC Gene Record

VEGFC 7424 Druggable GenomeDrug Resistance

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

VGX-100 VEGFC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

AFLIBERCEPT VEGFC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20124951

Sources: PharmGKB

CONBERCEPT VEGFC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Vascular endothelial growth factor C inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

BEVACIZUMAB VEGFC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20124951

Sources: ClearityFoundationClinicalTrial PharmGKB

LENALIDOMIDE VEGFC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: ClearityFoundationClinicalTrial

SUNITINIB VEGFC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21787417

Sources: CIViC

Ensembl: ENSG00000150630

Alternate Names: VEGFC Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: VEGFC

Alternate Names: PA37304 PharmGKB ID

Gene Info:

Publications: Maitland ML et al., 2010, Vascular endothelial growth factor pathway., Pharmacogenet Genomics

CIViC: VEGFC

Alternate Names: 7424 Entrez Gene ID 6073 CIViC Gene ID

Gene Info:

Publications: Harmon CS et al., 2011, Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib., J Transl Med

ChemblInteractions: VEGFC

Alternate Names: VEGFC GENE_SYMBOL Vascular endothelial growth factor C UNIPROT Flt4 ligand UNIPROT

Gene Info:

Publications:

HingoraniCasas: ENSG00000150630

Alternate Names: ENSG00000150630 Gene Symbol VEGFC Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

HumanProteinAtlas: VEGFC

Alternate Names: ENSG00000150630 Ensembl Gene ID VRP Human Protein Atlas Gene Synonym Vascular endothelial growth factor C Human Protein Atlas Gene Description

Gene Info:

Gene Categories: TRANSPORTER

Publications:

TTD: Vascular endothelial growth factor C

Alternate Names: VEGFC TTD Gene Abbreviation T51425 TTD Target ID

Gene Info:

Publications:

ClearityFoundationClinicalTrial: VEGFC

Alternate Names:

Gene Info:

Publications:

MyCancerGenomeClinicalTrial: VEGFC

Alternate Names:

Gene Info:

Publications:

GO: VEGFC

Alternate Names:

Gene Info:

Gene Categories: GROWTH FACTOR, DRUG RESISTANCE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
20124951

Sources:
PharmGKB

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vascular endothelial growth factor C inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
20124951

Sources:
ClearityFoundationClinicalTrial PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
ClearityFoundationClinicalTrial

Interaction Types & Directionality:

n/a

PMIDs:
21787417

Sources:
CIViC

Alternate Names:

VEGFC Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PA37304 PharmGKB ID

Publications:

Maitland ML et al., 2010, Vascular endothelial growth factor pathway., Pharmacogenet Genomics

Alternate Names:

7424 Entrez Gene ID

6073 CIViC Gene ID

Publications:

Harmon CS et al., 2011, Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib., J Transl Med

Alternate Names:

VEGFC GENE_SYMBOL

Vascular endothelial growth factor C UNIPROT

Flt4 ligand UNIPROT

Alternate Names:

ENSG00000150630 Gene Symbol

VEGFC Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000150630 Ensembl Gene ID

VRP Human Protein Atlas Gene Synonym

Vascular endothelial growth factor C Human Protein Atlas Gene Description

Gene Categories:

TRANSPORTER

Alternate Names:

VEGFC TTD Gene Abbreviation

T51425 TTD Target ID

Gene Categories:

GROWTH FACTOR, DRUG RESISTANCE