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VDAC1 Gene Record

  • Summary
  • Interactions
  • Claims
  • VDAC1 7416

    Alternate Names:

    7416
    VOLTAGE DEPENDENT ANION CHANNEL 1
    VDAC1
    PORIN
    VDAC-1
    604492
    12669
    ENSG00000213585
    OTTHUMG00000129118
    P21796
    BE0002468
    Voltage-dependent anion-selective channel 1
    T99397

    Gene Info:

    Target Class Transporters
    Target Subclass TC:1.B.8
    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics
    Zhang et al., 1990, Group IIIA-metal hydroxides indirectly neutralize the voltage sensor of the voltage-dependent mitochondrial channel, VDAC, by interacting with a dynamic binding site., Biochim. Biophys. Acta
    Zhang et al., 1989, Inhibition by aluminum hydroxide of the voltage-dependent closure of the mitochondrial channel, VDAC., Biochim. Biophys. Acta
  • CHEMBL3185220   VDAC1

    Interaction Score: 10.65

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    1694685 2469483


    Sources:
    DrugBank

  • OLESOXIME   VDAC1

    Interaction Score: 3.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name olesoxime, TRO19622
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • CANNABIDIOL   VDAC1

    Interaction Score: 0.66

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26264914


    Sources:
    DrugBank

  • NABIXIMOLS   VDAC1

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26264914


    Sources:
    DrugBank

  • Ensembl: ENSG00000213585

    • Version: 101_38

    Alternate Names:
    VDAC1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P21796

    • Version: January-2014

    Alternate Names:
    VDAC1 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:1.B.8

    Publications:

  • DrugBank: BE0002468

    • Version: 5.1.7

    Alternate Names:
    VDAC1 DrugBank Gene Name
    P21796 UniProt Accession
    7416 Entrez Gene Id

    Gene Info:

    Publications:
    Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics
    Zhang et al., 1990, Group IIIA-metal hydroxides indirectly neutralize the voltage sensor of the voltage-dependent mitochondrial channel, VDAC, by interacting with a dynamic binding site., Biochim. Biophys. Acta
    Zhang et al., 1989, Inhibition by aluminum hydroxide of the voltage-dependent closure of the mitochondrial channel, VDAC., Biochim. Biophys. Acta

  • TTD: Voltage-dependent anion-selective channel 1

    • Version: 2020.06.01

    Alternate Names:
    VDAC1 TTD Gene Abbreviation
    T99397 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21