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UCP2 Gene Record

  • Summary
  • Interactions
  • Claims
  • UCP2 7351 Druggable Genome

    Alternate Names:

    7351
    UNCOUPLING PROTEIN 2
    UCP2
    BMIQ4
    SLC25A8
    UCPH
    601693
    12518
    ENSG00000175567
    OTTHUMG00000168095
    MITOCHONDRIAL UNCOUPLING PROTEIN 2 (UCP 2) (UCPH). [SOURCE:UNIPROT/SWISSPROT;ACC:P55851]
    P55851
    Mitochondrial uncoupling protein 2
    T84560

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    DRUGGABLE GENOME

    Publications:

    Nisoli et al., 2000, Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion., Diabetes
    Masaki et al., 1997, Enhanced expression of uncoupling protein 2 gene in rat white adipose tissue and skeletal muscle following chronic treatment with thyroid hormone., FEBS Lett.
    Jekabsons et al., 1999, T(3) stimulates resting metabolism and UCP-2 and UCP-3 mRNA but not nonphosphorylating mitochondrial respiration in mice., Am. J. Physiol.
  • SOYBEAN OIL   UCP2

    Interaction Score: 6.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10868951


    Sources:
    NCI

  • SODIUM CHLORIDE   UCP2

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10868951


    Sources:
    NCI

  • LIOTHYRONINE SODIUM   UCP2

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9428737 10444435


    Sources:
    NCI

  • HEPARIN   UCP2

    Interaction Score: 1.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10868951


    Sources:
    NCI

  • Ensembl: ENSG00000175567

    • Version: 101_38

    Alternate Names:
    UCP2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000175567

    • Version: 26-July-2011

    Alternate Names:
    UCP2 Display Id
    ENSG00000175567 Ensembl Gene Id
    MITOCHONDRIAL UNCOUPLING PROTEIN 2 (UCP 2) (UCPH). [SOURCE:UNIPROT/SWISSPROT;ACC:P55851] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • NCI: UCP2

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Nisoli et al., 2000, Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion., Diabetes
    Sokolova et al., 2005, Evolution of mitochondrial uncoupling proteins: novel invertebrate UCP homologues suggest early evolutionary divergence of the UCP family., FEBS Lett.
    Aubert et al., 1997, Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells., Biochem. Biophys. Res. Commun.

  • TTD: Mitochondrial uncoupling protein 2

    • Version: 2020.06.01

    Alternate Names:
    UCP2 TTD Gene Abbreviation
    T84560 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: UCP2

    • Version: 01-February-2022

    Alternate Names:
    Mitochondrial uncoupling protein 2 Gene Name
    P55851 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21