• TYRO3 7301 Druggable GenomeClinically Actionable

    Alternate Names:

    7301
    TYRO3 PROTEIN TYROSINE KINASE
    TYRO3
    BYK
    Dtk
    Etk-2
    RSE
    Rek
    Sky
    Tif
    600341
    12446
    ENSG00000092445
    OTTHUMG00000130341
    1836
    Q06418
    TYRO3_HUMAN
    TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RSE) (TYROSINE-PROTEIN KINASE SKY) (TYROSINE- PROTEIN KINASE DTK) (PROTEIN-TYROSINE KINASE BYK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q06418]
    TYROSINE-PROTEIN KINASE RECEPTOR TYRO3
    NP_006284
    NM_006293
    TYRO3 tyrosine kinase receptor
    T94880
    BE0009404

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR001245
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Human Readable Name KINASE
    GuideToPharmacology Gene Category Name Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family
    GuideToPharmacology Gene Category ID 328
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
  • Interaction Score: 0.95

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

    • Version: 101_38

    Alternate Names:
    TYRO3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    TYRO3 Display Id
    TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RSE) (TYROSINE-PROTEIN KINASE SKY) (TYROSINE- PROTEIN KINASE DTK) (PROTEIN-TYROSINE KINASE BYK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q06418] Description
    ENSG00000092445 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    TYRO3_HUMAN Uniprot Id
    ENSG00000092445 Ensembl Gene Id
    TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 Uniprot Protein Name

    Gene Info:
    Interpro Acc IPR001245
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Uniprot Status Swiss-Prot

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    12446 HUGO Gene ID
    12446 HUGO Gene Symbol
    TYRO3 protein tyrosine kinase HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family
    GuideToPharmacology Gene Category ID 328

    Publications:

    • Version: 5.1.7

    Alternate Names:
    TYRO3 DrugBank Gene Name
    Q06418 UniProt Accession
    7301 Entrez Gene Id

    Gene Info:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000092445 Gene Symbol
    TYRO3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Tyrosine-protein kinase receptor TYRO3 Gene Name
    Q06418 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    BYK GO Gene Synonym
    DTK GO Gene Synonym
    RSE GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, TYROSINE KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    7301 Gene ID
    BYK dGene Synonym
    Dtk dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    TYRO3 TTD Gene Abbreviation
    T94880 TTD Target ID

    Gene Info:

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: