DGIdb - TPSB2 Gene Record

TPSB2 64499 Druggable Genome

Alternate Names:

64499
TRYPTASE BETA 2 (GENE/PSEUDOGENE)
TPSB2
TPS2
tryptaseB
tryptaseC
191081
14120
ENSG00000197253
OTTHUMG00000155926
P20231
TRYB2_HUMAN
64499; 7177
TRYPTASE BETA-2
ENSG00000172236
TRYPTASE BETA-1 PRECURSOR (EC 3.4.21.59) (TRYPTASE 1) (TRYPTASE I). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15661]
TRYPTASE BETA 2

Gene Info:

Human Readable Name	PROTEASE
Human Readable Name	DRUGGABLE GENOME
Uniprot Evidence	1: Evidence at protein level
Uniprot Status	Swiss-Prot
Interpro Acc	IPR001254
Interpro Short Name	Peptidase_S1_S6
Interpro Name	Peptidase S1/S6, chymotrypsin/Hap
Interpro Type	Domain
Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

PROTEASE
DRUGGABLE GENOME

Publications:

Harvima et al., 1988, The allosteric effect of salt on human mast cell tryptase., Biochim. Biophys. Acta
Hallgren et al., 2004, Histidines are critical for heparin-dependent activation of mast cell tryptase., J. Immunol.

VOLANESORSEN SODIUM TPSB2

Interaction Score: 5.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3048411

Sources:
NCI
HEPARIN TPSB2

Interaction Score: 2.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15265919

Sources:
NCI

Ensembl: ENSG00000197253
- Version: 101_38
Alternate Names:

TPSB2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P20231
- Version: 11-September-2012
Alternate Names:

P20231 Uniprot Accession

TPSB2 Uniprot Gene Name

TRYB2_HUMAN Uniprot Id

Gene Info:

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Uniprot Status Swiss-Prot

Gene Categories:

PROTEASE, DRUGGABLE GENOME

Publications:
RussLampel: ENSG00000197253
- Version: 26-July-2011
Alternate Names:

ENSG00000197253 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
RussLampel: ENSG00000172236
- Version: 26-July-2011
Alternate Names:

ENSG00000172236 Ensembl Gene Id

TPSB2 Display Id

TRYPTASE BETA-1 PRECURSOR (EC 3.4.21.59) (TRYPTASE 1) (TRYPTASE I). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15661] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

NCI: TPSB2

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Harvima et al., 1988, The allosteric effect of salt on human mast cell tryptase., Biochim. Biophys. Acta

Hallgren et al., 2004, Histidines are critical for heparin-dependent activation of mast cell tryptase., J. Immunol.

dGene: TPSB2
- Version: 27-Jun-2013
Alternate Names:

64499 Gene ID

TPS2 dGene Synonym

tryptaseB dGene Synonym

Gene Info:

Gene Categories:

PROTEASE

Publications:

P20231	Uniprot Accession
TPSB2	Uniprot Gene Name
TRYB2_HUMAN	Uniprot Id

ENSG00000172236	Ensembl Gene Id
TPSB2	Display Id
TRYPTASE BETA-1 PRECURSOR (EC 3.4.21.59) (TRYPTASE 1) (TRYPTASE I). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15661]	Description

64499	Gene ID
TPS2	dGene Synonym
tryptaseB	dGene Synonym

TPSB2 Gene Record

TPSB2 64499 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

VOLANESORSEN SODIUM TPSB2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3048411

Sources: NCI

HEPARIN TPSB2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15265919

Sources: NCI

Ensembl: ENSG00000197253

Alternate Names: TPSB2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: P20231

Alternate Names: P20231 Uniprot Accession TPSB2 Uniprot Gene Name TRYB2_HUMAN Uniprot Id

Gene Info: Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot

Gene Categories: PROTEASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000197253

Alternate Names: ENSG00000197253 Ensembl Gene Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000172236

Alternate Names: ENSG00000172236 Ensembl Gene Id TPSB2 Display Id TRYPTASE BETA-1 PRECURSOR (EC 3.4.21.59) (TRYPTASE 1) (TRYPTASE I). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15661] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

NCI: TPSB2

Alternate Names:

Gene Info:

Publications: Harvima et al., 1988, The allosteric effect of salt on human mast cell tryptase., Biochim. Biophys. Acta Hallgren et al., 2004, Histidines are critical for heparin-dependent activation of mast cell tryptase., J. Immunol.

dGene: TPSB2

Alternate Names: 64499 Gene ID TPS2 dGene Synonym tryptaseB dGene Synonym

Gene Info:

Gene Categories: PROTEASE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
3048411

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15265919

Sources:
NCI

Alternate Names:

TPSB2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

P20231 Uniprot Accession

TPSB2 Uniprot Gene Name

TRYB2_HUMAN Uniprot Id

Gene Info:

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Uniprot Status Swiss-Prot

Gene Categories:

PROTEASE, DRUGGABLE GENOME

Alternate Names:

ENSG00000197253 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000172236 Ensembl Gene Id

TPSB2 Display Id

TRYPTASE BETA-1 PRECURSOR (EC 3.4.21.59) (TRYPTASE 1) (TRYPTASE I). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15661] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

Harvima et al., 1988, The allosteric effect of salt on human mast cell tryptase., Biochim. Biophys. Acta

Hallgren et al., 2004, Histidines are critical for heparin-dependent activation of mast cell tryptase., J. Immunol.

Alternate Names:

64499 Gene ID

TPS2 dGene Synonym

tryptaseB dGene Synonym

Gene Categories:

PROTEASE