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TPSAB1 Gene Record

  • Summary
  • Interactions
  • Claims
  • TPSAB1 7177 Druggable Genome

    Alternate Names:

    7177
    TRYPTASE ALPHA/BETA 1
    TPSAB1
    TPS1
    TPS2
    TPSB1
    191080
    12019
    ENSG00000172236
    OTTHUMG00000090467
    Q15661
    TRYB1_HUMAN
    TRYPTASE ALPHA/BETA-1
    Tryptase
    T14558
    TPSB2
    Tryptase-2

    Gene Info:

    Human Readable Name PROTEASE
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Peptidase S1/S6, chymotrypsin/Hap
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Peptidase_S1_S6
    Interpro Acc IPR001254
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME

    Publications:

    Molino et al., 1997, Interactions of mast cell tryptase with thrombin receptors and PAR-2., J. Biol. Chem.
    Welker et al., GM-CSF downregulates expression of tryptase, Fc epsilon RI and histamine in HMC-1 mast cells., Int. Arch. Allergy Immunol.
  • PENTAMIDINE   TPSAB1

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • REGRAMOSTIM   TPSAB1

    Interaction Score: 2.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9130550


    Sources:
    NCI

  • THROMBIN   TPSAB1

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9020112


    Sources:
    NCI

  • Ensembl: ENSG00000172236

    • Version: 101_38

    Alternate Names:
    TPSAB1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q15661

    • Version: 11-September-2012

    Alternate Names:
    TPSAB1 Uniprot Gene Name
    ENSG00000172236 Ensembl Gene Id
    TRYB1_HUMAN Uniprot Id

    Gene Info:
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

  • NCI: TPSAB1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Molino et al., 1997, Interactions of mast cell tryptase with thrombin receptors and PAR-2., J. Biol. Chem.
    Welker et al., GM-CSF downregulates expression of tryptase, Fc epsilon RI and histamine in HMC-1 mast cells., Int. Arch. Allergy Immunol.

  • HingoraniCasas: ENSG00000172236

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000172236 Gene Symbol
    TPSAB1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: TPSAB1

    • Version: 27-Jun-2013

    Alternate Names:
    7177 Gene ID
    TPS1 dGene Synonym
    TPS2 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • TTD: Tryptase alpha/beta-1

    • Version: 2020.06.01

    Alternate Names:
    Tryptase TTD Gene Abbreviation
    T14558 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21