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TPH2 121278 Druggable Genome
Alternate Names:
121278 TRYPTOPHAN HYDROXYLASE 2 TPH2 ADHD7 NTPH 607478 20692 ENSG00000139287 OTTHUMG00000169677 TRYPTOPHAN 5-HYDROXYLASE 2 (EC 1.14.16.4) (TRYPTOPHAN 5-MONOOXYGENASE 2) (NEURONAL TRYPTOPHAN HYDROXYLASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8IWU9] BE0000080 Q8IWU9 Tryptophan 5-monooxygenase 2 Tryptophan 5-hydroxylase 2 Neuronal tryptophan hydroxylase PA128747823 TPH2_HUMAN L-Tryptophan hydroxylase 2 1242 Gene Info:
Human Readable Name DRUGGABLE GENOME Interpro Short Name ArAA_hydroxylase Uniprot Evidence 1: Evidence at protein level Interpro Name Aromatic amino acid hydroxylase Uniprot Status Swiss-Prot Interpro Type Family Interpro Acc IPR001273 Gene Biotype PROTEIN_CODING GuideToPharmacology Gene Category Name Amino acid hydroxylases GuideToPharmacology Gene Category ID 249 Gene Categories: Category Details
DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 3.55
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Score: 3.55
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Tryptophan 5-hydroxylase inhibitor -
Interaction Score: 3.55
Interaction Types & Directionality:
antagonist (inhibitory) inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Tryptophan 5-hydroxylase inhibitor -
Interaction Score: 1.78
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Score: 1.18
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Score: 0.89
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Interaction Score: 0.65
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Interaction Score: 0.41
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- Version: 101_38
Alternate Names:
TPH2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000139287 Ensembl Gene Id TRYPTOPHAN 5-HYDROXYLASE 2 (EC 1.14.16.4) (TRYPTOPHAN 5-MONOOXYGENASE 2) (NEURONAL TRYPTOPHAN HYDROXYLASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8IWU9] Description TPH2 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
TRYPTOPHAN 5-HYDROXYLASE 2 Uniprot Protein Name Q8IWU9 Uniprot Accession TPH2 Uniprot Gene Name Gene Info:
Interpro Short Name ArAA_hydroxylase Human Readable Name DRUGGABLE GENOME Uniprot Evidence 1: Evidence at protein level Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
20692 HUGO Gene ID 20692 HUGO Gene Symbol tryptophan hydroxylase 2 HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Amino acid hydroxylases GuideToPharmacology Gene Category ID 249 Gene Categories:
ENZYME Publications:
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Alternate Names:
PA128747823 PharmGKB ID Gene Info:
Publications:
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Alternate Names:
TPH2 DrugBank Gene Name Q8IWU9 UniProt Accession 121278 Entrez Gene Id Gene Info:
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- Version: chembl_23
Alternate Names:
NTPH GENE_SYMBOL TPH2 GENE_SYMBOL Tryptophan 5-hydroxylase 2 UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000139287 Gene Symbol TPH2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications: