DGIdb - TNFAIP6 Gene Record

TNFAIP6 7130 Druggable Genome

Alternate Names:

7130
TNF ALPHA INDUCED PROTEIN 6
TNFAIP6
TSG-6
TSG6
600410
11898
ENSG00000123610
OTTHUMG00000131884
BE0004952
P98066

Gene Info:

Gene Biotype	PROTEIN_CODING

(0 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME

Publications:

Wisniewski et al., 1994, TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor., Biochemistry
Lee et al., 1992, A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44., J. Cell Biol.
Kohda et al., 1996, Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration., Cell
Hwang J et al., 2010, Microglia signaling as a target of donepezil., Neuropharmacology

HYALURONATE SODIUM TNFAIP6

Interaction Score: 7.57

Interaction Types & Directionality:

binder

Interaction Info:

PMIDs:
7516184 1730767 8797823

Sources:
DrugBank
DONEPEZIL TNFAIP6

Interaction Score: 4.37

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
20153342

Sources:
DrugBank

Ensembl: ENSG00000123610
- Version: 101_38
Alternate Names:

TNFAIP6 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0004952

Version: 5.1.7

Alternate Names:

TNFAIP6 DrugBank Gene Name

P98066 UniProt Accession

7130 Entrez Gene Id

Gene Info:

Publications:

Jiang DQ et al., 2009, Aspirin inhibits tumor necrosis factor-alpha-stimulated fractalkine expression in human umbilical vein endothelial cells., Chin Med J (Engl)

Kim J et al., 2017, Aspirin prevents TNF-α-induced endothelial cell dysfunction by regulating the NF-κB-dependent miR-155/eNOS pathway: Role of a miR-155/eNOS axis in preeclampsia., Free Radic Biol Med

Kutuk O et al., 2004, Aspirin inhibits TNFalpha- and IL-1-induced NF-kappaB activation and sensitizes HeLa cells to apoptosis., Cytokine

HingoraniCasas: ENSG00000123610
- Version: 31-May-2017
Alternate Names:

ENSG00000123610 Gene Symbol

TNFAIP6 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications: