DGIdb - TK1 Gene Record

TK1 7083 Druggable Genome

Alternate Names:

7083
THYMIDINE KINASE 1
TK1
TK2
188300
11830
ENSG00000167900
OTTHUMG00000150674
KITH_HUMAN
P04183
BE0001260
THYMIDINE KINASE, CYTOSOLIC (EC 2.7.1.21). [SOURCE:UNIPROT/SWISSPROT;ACC:P04183]
THYMIDINE KINASE, CYTOSOLIC
PA352
T30081

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Interpro Short Name	Thymidine_kinase
Human Readable Name	KINASE
Interpro Acc	IPR001267
Uniprot Status	Swiss-Prot
Uniprot Evidence	1: Evidence at protein level
Interpro Name	Thymidine kinase
Interpro Type	Family
Gene Biotype	PROTEIN_CODING

(4 More Sources)

Gene Categories: Category Details

KINASE
DRUGGABLE GENOME
ENZYME

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

CHEMBL1232391 TK1

Interaction Score: 21.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423

Sources:
DrugBank
DEOXYTHYMIDINE_TRIPHOSPHATE TK1

Interaction Score: 10.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423

Sources:
DrugBank
ARGININE BUTYRATE TK1

Interaction Score: 7.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
PENCICLOVIR TK1

Interaction Score: 7.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
VALNIVUDINE HYDROCHLORIDE TK1

Interaction Score: 7.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
RILAPLADIB TK1

Interaction Score: 2.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
DEOXYCYTIDINE TK1

Interaction Score: 1.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
ZIDOVUDINE TK1

Interaction Score: 0.44

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22960662

Sources:
PharmGKB

Ensembl: ENSG00000167900
- Version: 101_38
Alternate Names:

TK1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P04183
- Version: 11-September-2012
Alternate Names:

KITH_HUMAN Uniprot Id

P04183 Uniprot Accession

ENSG00000167900 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Short Name Thymidine_kinase

Human Readable Name KINASE

Gene Categories:

KINASE, DRUGGABLE GENOME

Publications:
RussLampel: ENSG00000167900
- Version: 26-July-2011
Alternate Names:

ENSG00000167900 Ensembl Gene Id

TK1 Display Id

THYMIDINE KINASE, CYTOSOLIC (EC 2.7.1.21). [SOURCE:UNIPROT/SWISSPROT;ACC:P04183] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
PharmGKB: TK1
- Version: 18-August-2020
Alternate Names:

PA352 PharmGKB ID

Gene Info:

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics
DrugBank: BE0001260
- Version: 5.1.7
Alternate Names:

TK1 DrugBank Gene Name

P04183 UniProt Accession

7083 Entrez Gene Id

Gene Info:

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
HingoraniCasas: ENSG00000167900
- Version: 31-May-2017
Alternate Names:

ENSG00000167900 Gene Symbol

TK1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: TK1
- Version: 03-September-2020
Alternate Names:

P04183 UniProt ID

Thymidine kinase, cytosolic Gene Name

Gene Info:

Gene Categories:

KINASE, ENZYME

Publications:
TTD: Thymidine kinase 1
- Version: 2020.06.01
Alternate Names:

TK1 TTD Gene Abbreviation

T30081 TTD Target ID

Gene Info:

Publications:

KITH_HUMAN	Uniprot Id
P04183	Uniprot Accession
ENSG00000167900	Ensembl Gene Id

ENSG00000167900	Ensembl Gene Id
TK1	Display Id
THYMIDINE KINASE, CYTOSOLIC (EC 2.7.1.21). [SOURCE:UNIPROT/SWISSPROT;ACC:P04183]	Description

TK1	DrugBank Gene Name
P04183	UniProt Accession
7083	Entrez Gene Id

TK1 Gene Record

TK1 7083 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22960662

Sources: PharmGKB

Ensembl: ENSG00000167900

Alternate Names: TK1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: P04183

Alternate Names: KITH_HUMAN Uniprot Id P04183 Uniprot Accession ENSG00000167900 Ensembl Gene Id

Gene Info: Human Readable Name DRUGGABLE GENOME Interpro Short Name Thymidine_kinase Human Readable Name KINASE

Gene Categories: KINASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000167900

Alternate Names: ENSG00000167900 Ensembl Gene Id TK1 Display Id THYMIDINE KINASE, CYTOSOLIC (EC 2.7.1.21). [SOURCE:UNIPROT/SWISSPROT;ACC:P04183] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

PharmGKB: TK1

Alternate Names: PA352 PharmGKB ID

Gene Info:

Publications: Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

DrugBank: BE0001260

Alternate Names: TK1 DrugBank Gene Name P04183 UniProt Accession 7083 Entrez Gene Id

Gene Info:

Publications: Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

HingoraniCasas: ENSG00000167900

Alternate Names: ENSG00000167900 Gene Symbol TK1 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

Pharos: TK1

Alternate Names: P04183 UniProt ID Thymidine kinase, cytosolic Gene Name

Gene Info:

Gene Categories: KINASE, ENZYME

Publications:

TTD: Thymidine kinase 1

Alternate Names: TK1 TTD Gene Abbreviation T30081 TTD Target ID

Gene Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
22960662

Sources:
PharmGKB

Alternate Names:

TK1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

KITH_HUMAN Uniprot Id

P04183 Uniprot Accession

ENSG00000167900 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Short Name Thymidine_kinase

Human Readable Name KINASE

Gene Categories:

KINASE, DRUGGABLE GENOME

Alternate Names:

ENSG00000167900 Ensembl Gene Id

TK1 Display Id

THYMIDINE KINASE, CYTOSOLIC (EC 2.7.1.21). [SOURCE:UNIPROT/SWISSPROT;ACC:P04183] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

PA352 PharmGKB ID

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

Alternate Names:

TK1 DrugBank Gene Name

P04183 UniProt Accession

7083 Entrez Gene Id

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

ENSG00000167900 Gene Symbol

TK1 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

P04183 UniProt ID

Thymidine kinase, cytosolic Gene Name

Gene Categories:

KINASE, ENZYME

Alternate Names:

TK1 TTD Gene Abbreviation

T30081 TTD Target ID