DGIdb - THBS1 Gene Record

THBS1 7057 Druggable Genome

Alternate Names:

7057
THROMBOSPONDIN 1
THBS1
THBS
THBS-1
TSP
TSP-1
TSP1
188060
11785
ENSG00000137801
OTTHUMG00000133665
Thrombospondin-1
T30784
P07996

Gene Info:

Gene Biotype	PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

CELL SURFACE
EXTERNAL SIDE OF PLASMA MEMBRANE
DRUGGABLE GENOME
TRANSCRIPTION FACTOR

Publications:

Chen et al., 1997, Thrombospondin, a negative modulator of megakaryocytopoiesis., J. Lab. Clin. Med.
Riessen et al., 1999, Effect of HMG-CoA reductase inhibitors on extracellular matrix expression in human vascular smooth muscle cells., Basic Res. Cardiol.
Truter et al., Vesnarinone-mediated alterations of gene expression in cardiac fibroblasts from aortic regurgitant hearts., Am J Ther
Lafeuillade et al., 1996, Opposite regulation of thrombospondin-1 and corticotropin-induced secreted protein/thrombospondin-2 expression by adrenocorticotropic hormone in adrenocortical cells., J. Cell. Physiol.
Wang et al., 2006, [Effects of pioglitazone on MKP-1 and TSP-1 expression in early stages of diabetic retinopathy induced by streptozotocin]., Zhejiang Da Xue Xue Bao Yi Xue Ban
Rath et al., 2006, The C-terminal CD47/IAP-binding domain of thrombospondin-1 prevents camptothecin- and doxorubicin-induced apoptosis in human thyroid carcinoma cells., Biochim. Biophys. Acta

METHYLCELLULOSE THBS1

Interaction Score: 7.73

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9016860

Sources:
NCI
VESNARINONE THBS1

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15356428

Sources:
NCI
ABT-510 THBS1

Interaction Score: 1.93

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
CORTICOTROPIN THBS1

Interaction Score: 1.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8698834

Sources:
NCI
PIOGLITAZONE THBS1

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17063547

Sources:
NCI
CAMPTOTHECIN THBS1

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16962673

Sources:
NCI
LOVASTATIN THBS1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10543307

Sources:
NCI
SIMVASTATIN THBS1

Interaction Score: 0.29

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10543307

Sources:
NCI

Ensembl: ENSG00000137801
- Version: 101_38
Alternate Names:

THBS1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

NCI: THBS1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Crombie et al., 1998, Identification of a CD36-related thrombospondin 1-binding domain in HIV-1 envelope glycoprotein gp120: relationship to HIV-1-specific inhibitory factors in human saliva., J. Exp. Med.

Chua et al., 1997, Regulation of thrombospondin-1 production by angiotensin II in rat heart endothelial cells., Biochim. Biophys. Acta

Yano et al., 2004, Ultraviolet B-induced skin angiogenesis is associated with a switch in the balance of vascular endothelial growth factor and thrombospondin-1 expression., J. Invest. Dermatol.

HingoraniCasas: ENSG00000137801
- Version: 31-May-2017
Alternate Names:

ENSG00000137801 Gene Symbol

THBS1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
TALC: THBS1
- Version: 12-May-2016
Alternate Names:

THBS1 Gene Symbol

Gene Info:

Publications:
GO: THBS1
- Version: 01-February-2022
Alternate Names:

TSP GO Gene Synonym

TSP1 GO Gene Synonym

Gene Info:

Gene Categories:

CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:
TTD: Thrombospondin-1
- Version: 2020.06.01
Alternate Names:

THBS1 TTD Gene Abbreviation

T30784 TTD Target ID

Gene Info:

Publications:
Pharos: THBS1
- Version: 01-February-2022
Alternate Names:

Thrombospondin-1 Gene Name

P07996 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications:

THBS1	TTD Gene Abbreviation
T30784	TTD Target ID

THBS1 Gene Record

THBS1 7057 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9016860

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15356428

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8698834

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17063547

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16962673

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10543307

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10543307

Sources: NCI

Ensembl: ENSG00000137801

Alternate Names: THBS1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

NCI: THBS1

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000137801

Alternate Names: ENSG00000137801 Gene Symbol THBS1 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

TALC: THBS1

Alternate Names: THBS1 Gene Symbol

Gene Info:

Publications:

GO: THBS1

Alternate Names: TSP GO Gene Synonym TSP1 GO Gene Synonym

Gene Info:

Gene Categories: CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

TTD: Thrombospondin-1

Alternate Names: THBS1 TTD Gene Abbreviation T30784 TTD Target ID

Gene Info:

Publications:

Pharos: THBS1

Alternate Names: Thrombospondin-1 Gene Name P07996 UniProt ID

Gene Info:

Gene Categories: TRANSCRIPTION FACTOR

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
9016860

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15356428

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
8698834

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
17063547

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16962673

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10543307

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10543307

Sources:
NCI

Alternate Names:

THBS1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000137801 Gene Symbol

THBS1 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

THBS1 Gene Symbol

Alternate Names:

TSP GO Gene Synonym

TSP1 GO Gene Synonym

Gene Categories:

CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

Alternate Names:

THBS1 TTD Gene Abbreviation

T30784 TTD Target ID

Alternate Names:

Thrombospondin-1 Gene Name

P07996 UniProt ID

Gene Categories:

TRANSCRIPTION FACTOR