DGIdb - TGM2 Gene Record

TGM2 7052 Druggable Genome

Alternate Names:

7052
TRANSGLUTAMINASE 2
TGM2
TG(C)
TGC
190196
11778
ENSG00000198959
OTTHUMG00000032437
BE0001035
P21980
TGM2_HUMAN
PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2
TISSUE TRANSGLUTAMINASE
PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE (EC 2.3.2.13) (TISSUE TRANSGLUTAMINASE) (TGASE C) (TGC) (TG(C)) (TRANGLUTAMINASE 2) (TGASE- H). [SOURCE:UNIPROT/SWISSPROT;ACC:P21980]
TG2
T05387
3015
NM_004613
NP_004604

Gene Info:

Interpro Type	Domain
Human Readable Name	DRUGGABLE GENOME
Interpro Short Name	Transglutaminase_N
Interpro Name	Transglutaminase, N-terminal
Uniprot Status	Swiss-Prot
Interpro Acc	IPR001102
Uniprot Evidence	1: Evidence at protein level
Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	2.3.2.13 Transglutaminases
GuideToPharmacology Gene Category ID	1003

(5 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
ENZYME

Publications:

Zhang et al., 1997, Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide., Life Sci.
Nardacci et al., 2005, Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis., Am. J. Pathol.
Hausch et al., 2003, Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase., Chem. Biol.
Nakano et al., 2007, ATP-mediated mineralization of MC3T3-E1 osteoblast cultures., Bone
Tschirch et al., 2007, Low-dose intranasal versus oral midazolam for routine body MRI of claustrophobic patients., Eur Radiol
Ai et al., 2008, The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer., Carcinogenesis
Balasenthil et al., 2002, Apoptosis induction by S-allylcysteine, a garlic constituent, during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis., Cell Biochem. Funct.
Osborne et al., 1997, Minor products of reaction of DNA with alpha-acetoxytamoxifen., Carcinogenesis
Soehnlein et al., 2004, Atorvastatin induces tissue transglutaminase in human endothelial cells., Biochem. Biophys. Res. Commun.
Kitahara et al., 1987, Specific localization of tissue-type transglutaminase in adrenocorticotropin-producing cells of the human pituitary gland as demonstrated by immunohistochemistry., J. Clin. Endocrinol. Metab.
Waldron et al., 1997, Store-operated Ca2+ entry and coupling to Ca2+ pool depletion in thapsigargin-resistant cells., J. Biol. Chem.
Cao et al., 2008, Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling., Carcinogenesis
Lin et al., 1998, Camptothecin induces differentiation, tissue transglutaminase and apoptosis in cultured keratinocytes., Exp. Dermatol.
Wu et al., 2000, Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction., J. Biol. Chem.
Adel Moallem et al., 1996, Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse., Biol. Reprod.
Zeng et al., 2005, [Enhancement of NMDA receptor sensitivity by thrombin and its relationship with tissue transglutaminase]., Zhonghua Nei Ke Za Zhi
Gambetti et al., 2005, Interaction with heparin protects tissue transglutaminase against inactivation by heating and by proteolysis., Biochimie
Ando et al., 1996, Induction of tissue transglutaminase in rat superior cervical sympathetic ganglia following in vitro stimulation of retinoic acid., Neurosci. Res.
Fujimoto et al., 1996, Requirement for transglutaminase in progesterone-induced decidualization of human endometrial stromal cells., Endocrinology
Verma et al., 2006, Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis., Cancer Res.
Rittmaster et al., 1995, Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride., Endocrinology
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

HEXYLRESORCINOL TGM2

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Publications:
DEFEROXAMINE TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Zhang et al., 1997, Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide., Life Sci.
SIROLIMUS TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Nardacci et al., 2005, Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis., Am. J. Pathol.
ACIVICIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Hausch et al., 2003, Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase., Chem. Biol.
LEVAMISOLE TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Nakano et al., 2007, ATP-mediated mineralization of MC3T3-E1 osteoblast cultures., Bone
MIDAZOLAM TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Tschirch et al., 2007, Low-dose intranasal versus oral midazolam for routine body MRI of claustrophobic patients., Eur Radiol
DOXORUBICIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Ai et al., 2008, The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer., Carcinogenesis
GARLIC TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Balasenthil et al., 2002, Apoptosis induction by S-allylcysteine, a garlic constituent, during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis., Cell Biochem. Funct.
TAMOXIFEN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Osborne et al., 1997, Minor products of reaction of DNA with alpha-acetoxytamoxifen., Carcinogenesis
ATORVASTATIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Soehnlein et al., 2004, Atorvastatin induces tissue transglutaminase in human endothelial cells., Biochem. Biophys. Res. Commun.

CORTICOTROPIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Kitahara et al., 1987, Specific localization of tissue-type transglutaminase in adrenocorticotropin-producing cells of the human pituitary gland as demonstrated by immunohistochemistry., J. Clin. Endocrinol. Metab.

IONOMYCIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Waldron et al., 1997, Store-operated Ca2+ entry and coupling to Ca2+ pool depletion in thapsigargin-resistant cells., J. Biol. Chem.
CISPLATIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Cao et al., 2008, Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling., Carcinogenesis
CAMPTOTHECIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Lin et al., 1998, Camptothecin induces differentiation, tissue transglutaminase and apoptosis in cultured keratinocytes., Exp. Dermatol.
ALCOHOL TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Wu et al., 2000, Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction., J. Biol. Chem.
PERFOSFAMIDE TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Adel Moallem et al., 1996, Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse., Biol. Reprod.
THROMBIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Zeng et al., 2005, [Enhancement of NMDA receptor sensitivity by thrombin and its relationship with tissue transglutaminase]., Zhonghua Nei Ke Za Zhi
HEPARIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Gambetti et al., 2005, Interaction with heparin protects tissue transglutaminase against inactivation by heating and by proteolysis., Biochimie
GENTAMICIN TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Ando et al., 1996, Induction of tissue transglutaminase in rat superior cervical sympathetic ganglia following in vitro stimulation of retinoic acid., Neurosci. Res.
PROGESTERONE TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Fujimoto et al., 1996, Requirement for transglutaminase in progesterone-induced decidualization of human endometrial stromal cells., Endocrinology
GEMCITABINE TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Verma et al., 2006, Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis., Cancer Res.
FINASTERIDE TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Rittmaster et al., 1995, Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride., Endocrinology
CHEMBL384759 TGM2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Ensembl: ENSG00000198959
- Version: 101_38
Alternate Names:

TGM2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000198959

Version: 26-July-2011

Alternate Names:

TGM2 Display Id

PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE (EC 2.3.2.13) (TISSUE TRANSGLUTAMINASE) (TGASE C) (TGC) (TG(C)) (TRANGLUTAMINASE 2) (TGASE- H). [SOURCE:UNIPROT/SWISSPROT;ACC:P21980] Description

ENSG00000198959 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

HopkinsGroom: P21980
- Version: 11-September-2012
Alternate Names:

TGM2 Uniprot Gene Name

PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 Uniprot Protein Name

TGM2_HUMAN Uniprot Id

Gene Info:

Interpro Type Domain

Human Readable Name DRUGGABLE GENOME

Interpro Short Name Transglutaminase_N

Gene Categories:

DRUGGABLE GENOME

Publications:
GuideToPharmacology: 7052
- Version: 29-September-2020
Alternate Names:

11778 HUGO Gene ID

11778 HUGO Gene Symbol

transglutaminase 2 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name 2.3.2.13 Transglutaminases

GuideToPharmacology Gene Category ID 1003

Gene Categories:

ENZYME

Publications:
DrugBank: BE0001035
- Version: 5.1.7
Alternate Names:

TGM2 DrugBank Gene Name

P21980 UniProt Accession

7052 Entrez Gene Id

Gene Info:

Publications:

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

NCI: TGM2

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Zhang et al., 1997, Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide., Life Sci.

Nardacci et al., 2005, Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis., Am. J. Pathol.

Nakano et al., 2007, ATP-mediated mineralization of MC3T3-E1 osteoblast cultures., Bone

HingoraniCasas: ENSG00000198959
- Version: 31-May-2017
Alternate Names:

ENSG00000198959 Gene Symbol

TGM2 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: TGM2
- Version: 03-September-2020
Alternate Names:

Protein-glutamine gamma-glutamyltransferase 2 Gene Name

P21980 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:
TTD: Tissue transglutaminase
- Version: 2020.06.01
Alternate Names:

TG2 TTD Gene Abbreviation

T05387 TTD Target ID

Gene Info:

Publications:

TGM2	Display Id
PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE (EC 2.3.2.13) (TISSUE TRANSGLUTAMINASE) (TGASE C) (TGC) (TG(C)) (TRANGLUTAMINASE 2) (TGASE- H). [SOURCE:UNIPROT/SWISSPROT;ACC:P21980]	Description
ENSG00000198959	Ensembl Gene Id

TGM2	Uniprot Gene Name
PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2	Uniprot Protein Name
TGM2_HUMAN	Uniprot Id

11778	HUGO Gene ID
11778	HUGO Gene Symbol
transglutaminase 2	HUGO Gene Name

TGM2	DrugBank Gene Name
P21980	UniProt Accession
7052	Entrez Gene Id

Protein-glutamine gamma-glutamyltransferase 2	Gene Name
P21980	UniProt ID

TGM2 Gene Record

TGM2 7052 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Zhang et al., 1997, Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide., Life Sci.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Nardacci et al., 2005, Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis., Am. J. Pathol.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Hausch et al., 2003, Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase., Chem. Biol.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Nakano et al., 2007, ATP-mediated mineralization of MC3T3-E1 osteoblast cultures., Bone

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Tschirch et al., 2007, Low-dose intranasal versus oral midazolam for routine body MRI of claustrophobic patients., Eur Radiol

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Ai et al., 2008, The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer., Carcinogenesis

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Balasenthil et al., 2002, Apoptosis induction by S-allylcysteine, a garlic constituent, during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis., Cell Biochem. Funct.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Osborne et al., 1997, Minor products of reaction of DNA with alpha-acetoxytamoxifen., Carcinogenesis

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Soehnlein et al., 2004, Atorvastatin induces tissue transglutaminase in human endothelial cells., Biochem. Biophys. Res. Commun.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Kitahara et al., 1987, Specific localization of tissue-type transglutaminase in adrenocorticotropin-producing cells of the human pituitary gland as demonstrated by immunohistochemistry., J. Clin. Endocrinol. Metab.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Waldron et al., 1997, Store-operated Ca2+ entry and coupling to Ca2+ pool depletion in thapsigargin-resistant cells., J. Biol. Chem.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Cao et al., 2008, Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling., Carcinogenesis

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Lin et al., 1998, Camptothecin induces differentiation, tissue transglutaminase and apoptosis in cultured keratinocytes., Exp. Dermatol.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Wu et al., 2000, Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction., J. Biol. Chem.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Adel Moallem et al., 1996, Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse., Biol. Reprod.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Zeng et al., 2005, [Enhancement of NMDA receptor sensitivity by thrombin and its relationship with tissue transglutaminase]., Zhonghua Nei Ke Za Zhi

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Gambetti et al., 2005, Interaction with heparin protects tissue transglutaminase against inactivation by heating and by proteolysis., Biochimie

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Ando et al., 1996, Induction of tissue transglutaminase in rat superior cervical sympathetic ganglia following in vitro stimulation of retinoic acid., Neurosci. Res.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Fujimoto et al., 1996, Requirement for transglutaminase in progesterone-induced decidualization of human endometrial stromal cells., Endocrinology

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Verma et al., 2006, Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis., Cancer Res.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Rittmaster et al., 1995, Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride., Endocrinology

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Ensembl: ENSG00000198959

Alternate Names: TGM2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000198959

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Types & Directionality:

n/a

Publications:

Zhang et al., 1997, Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide., Life Sci.

Interaction Types & Directionality:

n/a

Publications:

Nardacci et al., 2005, Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis., Am. J. Pathol.

Interaction Types & Directionality:

n/a

Publications:

Hausch et al., 2003, Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase., Chem. Biol.

Interaction Types & Directionality:

n/a

Publications:

Nakano et al., 2007, ATP-mediated mineralization of MC3T3-E1 osteoblast cultures., Bone

Interaction Types & Directionality:

n/a

Publications:

Tschirch et al., 2007, Low-dose intranasal versus oral midazolam for routine body MRI of claustrophobic patients., Eur Radiol

Interaction Types & Directionality:

n/a

Publications:

Ai et al., 2008, The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer., Carcinogenesis

Interaction Types & Directionality:

n/a

Publications:

Balasenthil et al., 2002, Apoptosis induction by S-allylcysteine, a garlic constituent, during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis., Cell Biochem. Funct.

Interaction Types & Directionality:

n/a

Publications:

Osborne et al., 1997, Minor products of reaction of DNA with alpha-acetoxytamoxifen., Carcinogenesis

Interaction Types & Directionality:

n/a

Publications:

Soehnlein et al., 2004, Atorvastatin induces tissue transglutaminase in human endothelial cells., Biochem. Biophys. Res. Commun.

Interaction Types & Directionality:

n/a

Publications:

Kitahara et al., 1987, Specific localization of tissue-type transglutaminase in adrenocorticotropin-producing cells of the human pituitary gland as demonstrated by immunohistochemistry., J. Clin. Endocrinol. Metab.

Interaction Types & Directionality:

n/a

Publications:

Waldron et al., 1997, Store-operated Ca2+ entry and coupling to Ca2+ pool depletion in thapsigargin-resistant cells., J. Biol. Chem.

Interaction Types & Directionality:

n/a

Publications:

Cao et al., 2008, Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling., Carcinogenesis

Interaction Types & Directionality:

n/a

Publications:

Lin et al., 1998, Camptothecin induces differentiation, tissue transglutaminase and apoptosis in cultured keratinocytes., Exp. Dermatol.

Interaction Types & Directionality:

n/a

Publications:

Wu et al., 2000, Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction., J. Biol. Chem.

Interaction Types & Directionality:

n/a

Publications:

Adel Moallem et al., 1996, Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse., Biol. Reprod.

Interaction Types & Directionality:

n/a

Publications:

Zeng et al., 2005, [Enhancement of NMDA receptor sensitivity by thrombin and its relationship with tissue transglutaminase]., Zhonghua Nei Ke Za Zhi

Interaction Types & Directionality:

n/a

Publications:

Gambetti et al., 2005, Interaction with heparin protects tissue transglutaminase against inactivation by heating and by proteolysis., Biochimie

Interaction Types & Directionality:

n/a

Publications:

Ando et al., 1996, Induction of tissue transglutaminase in rat superior cervical sympathetic ganglia following in vitro stimulation of retinoic acid., Neurosci. Res.

Interaction Types & Directionality:

n/a

Publications:

Fujimoto et al., 1996, Requirement for transglutaminase in progesterone-induced decidualization of human endometrial stromal cells., Endocrinology

Interaction Types & Directionality:

n/a

Publications:

Verma et al., 2006, Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis., Cancer Res.

Interaction Types & Directionality:

n/a

Publications:

Rittmaster et al., 1995, Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride., Endocrinology

Interaction Types & Directionality:

n/a

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

TGM2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

TGM2 Display Id

PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE (EC 2.3.2.13) (TISSUE TRANSGLUTAMINASE) (TGASE C) (TGC) (TG(C)) (TRANGLUTAMINASE 2) (TGASE- H). [SOURCE:UNIPROT/SWISSPROT;ACC:P21980] Description

ENSG00000198959 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

TGM2 Uniprot Gene Name

PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 Uniprot Protein Name

TGM2_HUMAN Uniprot Id

Gene Info:

Interpro Type Domain

Human Readable Name DRUGGABLE GENOME

Interpro Short Name Transglutaminase_N

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

11778 HUGO Gene ID

11778 HUGO Gene Symbol

transglutaminase 2 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name 2.3.2.13 Transglutaminases

GuideToPharmacology Gene Category ID 1003

Gene Categories:

ENZYME

Alternate Names:

TGM2 DrugBank Gene Name

P21980 UniProt Accession

7052 Entrez Gene Id

Publications:

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Alternate Names:

ENSG00000198959 Gene Symbol

TGM2 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

Protein-glutamine gamma-glutamyltransferase 2 Gene Name

P21980 UniProt ID

Gene Categories:

ENZYME

Alternate Names:

TG2 TTD Gene Abbreviation

T05387 TTD Target ID