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TEC Gene Record

  • Summary
  • Interactions
  • Claims
  • TEC 7006 Druggable GenomeClinically Actionable

    Alternate Names:

    7006
    TEC PROTEIN TYROSINE KINASE
    TEC
    PSCTK4
    600583
    11719
    ENSG00000135605
    OTTHUMG00000128623
    P42680
    TEC_HUMAN
    TYROSINE-PROTEIN KINASE TEC
    TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680]
    T15848

    Gene Info:

    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Type Domain
    Interpro Acc IPR001245
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Human Readable Name KINASE
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE

    Publications:

    Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.
    Hantschel O et al., 2007, The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib., Proc Natl Acad Sci U S A
  • INOSITOL   TEC

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9240435


    Sources:
    NCI

  • DASATINIB   TEC

    Interaction Score: 0.88

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17684099


    Sources:
    DTC

  • Ensembl: ENSG00000135605

    • Version: 101_38

    Alternate Names:
    TEC Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P42680

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000135605 Ensembl Gene Id
    7006 Entrez Gene Id
    TYROSINE-PROTEIN KINASE TEC Uniprot Protein Name

    Gene Info:
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Type Domain
    Interpro Acc IPR001245

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000135605

    • Version: 26-July-2011

    Alternate Names:
    TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680] Description
    ENSG00000135605 Ensembl Gene Id
    TEC Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • NCI: TEC

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.

  • DTC: TEC

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Hantschel O et al., 2007, The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib., Proc Natl Acad Sci U S A

  • HingoraniCasas: ENSG00000135605

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000135605 Gene Symbol
    TEC Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: TEC

    • Version: 01-February-2022

    Alternate Names:
    PSCTK4 GO Gene Synonym

    Gene Info:

    Gene Categories:
    TYROSINE KINASE

    Publications:

  • dGene: TEC

    • Version: 27-Jun-2013

    Alternate Names:
    7006 Gene ID
    PSCTK4 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • TTD: Tyrosine-protein kinase Tec

    • Version: 2020.06.01

    Alternate Names:
    PSCTK4 TTD Gene Abbreviation
    T15848 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: TEC

    • Version: 01-February-2022

    Alternate Names:
    Tyrosine-protein kinase Tec Gene Name
    P42680 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • FoundationOneGenes: TEC

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21