DGIdb - TEC Gene Record

TEC 7006 Druggable GenomeClinically Actionable

Alternate Names:

7006
TEC PROTEIN TYROSINE KINASE
TEC
PSCTK4
600583
11719
ENSG00000135605
OTTHUMG00000128623
P42680
TEC_HUMAN
TYROSINE-PROTEIN KINASE TEC
TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680]
T15848

Gene Info:

Interpro Short Name	Ser-Thr/Tyr_kinase_cat_dom
Interpro Type	Domain
Interpro Acc	IPR001245
Uniprot Evidence	1: Evidence at protein level
Interpro Name	Serine-threonine/tyrosine-protein kinase catalytic domain
Human Readable Name	KINASE
Human Readable Name	DRUGGABLE GENOME
Uniprot Status	Swiss-Prot
Gene Biotype	PROTEIN_CODING

(7 More Sources)

Gene Categories: Category Details

KINASE
TYROSINE KINASE
DRUGGABLE GENOME
CLINICALLY ACTIONABLE

Publications:

Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.
Hantschel O et al., 2007, The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib., Proc Natl Acad Sci U S A

INOSITOL TEC

Interaction Score: 4.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9240435

Sources:
NCI
DASATINIB TEC

Interaction Score: 0.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17684099

Sources:
DTC

Ensembl: ENSG00000135605
- Version: 101_38
Alternate Names:

TEC Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P42680
- Version: 11-September-2012
Alternate Names:

ENSG00000135605 Ensembl Gene Id

7006 Entrez Gene Id

TYROSINE-PROTEIN KINASE TEC Uniprot Protein Name

Gene Info:

Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom

Interpro Type Domain

Interpro Acc IPR001245

Gene Categories:

KINASE, DRUGGABLE GENOME

Publications:
RussLampel: ENSG00000135605
- Version: 26-July-2011
Alternate Names:

TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680] Description

ENSG00000135605 Ensembl Gene Id

TEC Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
NCI: TEC
- Version: 14-September-2017
Alternate Names:

Gene Info:

Publications:

Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.
DTC: TEC
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

Hantschel O et al., 2007, The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib., Proc Natl Acad Sci U S A
HingoraniCasas: ENSG00000135605
- Version: 31-May-2017
Alternate Names:

ENSG00000135605 Gene Symbol

TEC Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: TEC
- Version: 01-February-2022
Alternate Names:

PSCTK4 GO Gene Synonym

Gene Info:

Gene Categories:

TYROSINE KINASE

Publications:
dGene: TEC
- Version: 27-Jun-2013
Alternate Names:

7006 Gene ID

PSCTK4 dGene Synonym

Gene Info:

Gene Categories:

KINASE, TYROSINE KINASE

Publications:
TTD: Tyrosine-protein kinase Tec
- Version: 2020.06.01
Alternate Names:

PSCTK4 TTD Gene Abbreviation

T15848 TTD Target ID

Gene Info:

Publications:
Pharos: TEC
- Version: 01-February-2022
Alternate Names:

Tyrosine-protein kinase Tec Gene Name

P42680 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:
FoundationOneGenes: TEC
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:

ENSG00000135605	Ensembl Gene Id
7006	Entrez Gene Id
TYROSINE-PROTEIN KINASE TEC	Uniprot Protein Name

TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680]	Description
ENSG00000135605	Ensembl Gene Id
TEC	Display Id

PSCTK4	TTD Gene Abbreviation
T15848	TTD Target ID

TEC Gene Record

TEC 7006 Druggable GenomeClinically Actionable

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

INOSITOL TEC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9240435

Sources: NCI

DASATINIB TEC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17684099

Sources: DTC

Ensembl: ENSG00000135605

Alternate Names: TEC Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: P42680

Alternate Names: ENSG00000135605 Ensembl Gene Id 7006 Entrez Gene Id TYROSINE-PROTEIN KINASE TEC Uniprot Protein Name

Gene Info: Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom Interpro Type Domain Interpro Acc IPR001245

Gene Categories: KINASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000135605

Alternate Names: TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680] Description ENSG00000135605 Ensembl Gene Id TEC Display Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

NCI: TEC

Alternate Names:

Gene Info:

Publications: Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.

DTC: TEC

Alternate Names:

Gene Info:

Publications: Hantschel O et al., 2007, The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib., Proc Natl Acad Sci U S A

HingoraniCasas: ENSG00000135605

Alternate Names: ENSG00000135605 Gene Symbol TEC Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

GO: TEC

Alternate Names: PSCTK4 GO Gene Synonym

Gene Info:

Gene Categories: TYROSINE KINASE

Publications:

dGene: TEC

Alternate Names: 7006 Gene ID PSCTK4 dGene Synonym

Gene Info:

Gene Categories: KINASE, TYROSINE KINASE

Publications:

TTD: Tyrosine-protein kinase Tec

Alternate Names: PSCTK4 TTD Gene Abbreviation T15848 TTD Target ID

Gene Info:

Publications:

Pharos: TEC

Alternate Names: Tyrosine-protein kinase Tec Gene Name P42680 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

FoundationOneGenes: TEC

Alternate Names:

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
9240435

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
17684099

Sources:
DTC

Alternate Names:

TEC Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000135605 Ensembl Gene Id

7006 Entrez Gene Id

TYROSINE-PROTEIN KINASE TEC Uniprot Protein Name

Gene Info:

Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom

Interpro Type Domain

Interpro Acc IPR001245

Gene Categories:

KINASE, DRUGGABLE GENOME

Alternate Names:

TYROSINE-PROTEIN KINASE TEC (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P42680] Description

ENSG00000135605 Ensembl Gene Id

TEC Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.

Publications:

Hantschel O et al., 2007, The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib., Proc Natl Acad Sci U S A

Alternate Names:

ENSG00000135605 Gene Symbol

TEC Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

PSCTK4 GO Gene Synonym

Gene Categories:

TYROSINE KINASE

Alternate Names:

7006 Gene ID

PSCTK4 dGene Synonym

Gene Categories:

KINASE, TYROSINE KINASE

Alternate Names:

PSCTK4 TTD Gene Abbreviation

T15848 TTD Target ID

Alternate Names:

Tyrosine-protein kinase Tec Gene Name

P42680 UniProt ID

Gene Categories:

KINASE

Gene Categories:

CLINICALLY ACTIONABLE