DGIdb - STK3 Gene Record

STK3 6788 Druggable Genome

Alternate Names:

6788
SERINE/THREONINE KINASE 3
STK3
KRS1
MST2
605030
11406
ENSG00000104375
OTTHUMG00000164651
Q13188
STK3_HUMAN
SERINE/THREONINE-PROTEIN KINASE 3 (EC 2.7.1.37) (STE20-LIKE KINASE MST2) (MST-2) (MAMMALIAN STE20-LIKE PROTEIN KINASE 2) (SERINE/THREONINE-PROTEIN KINASE KRS-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13188]
SERINE/THREONINE-PROTEIN KINASE 3 36KDA SUBUNIT
Serine/threonine-protein kinase 3

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Interpro Type	Domain
Uniprot Status	Swiss-Prot
Interpro Acc	IPR002290
Uniprot Evidence	1: Evidence at protein level
Interpro Short Name	Ser/Thr_dual-sp_kinase_dom
Interpro Name	Serine/threonine- / dual-specificity protein kinase, catalytic domain
Human Readable Name	KINASE
Gene Biotype	PROTEIN_CODING

(5 More Sources)

Gene Categories: Category Details

KINASE
SERINE THREONINE KINASE
DRUGGABLE GENOME

Publications:

Kusakabe K et al., 2013, Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125)., J Med Chem
Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.

CHEMBL2005186 STK3

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
VATALANIB STK3

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LY-2090314 STK3

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LAUROGUADINE STK3

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SB-220025 STK3

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL541400 STK3

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GW843682X STK3

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HESPERADIN STK3

Interaction Score: 0.06

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
19035792

Sources:
DTC
CHEMBL379975 STK3

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SP-600125 STK3

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23634759

Sources:
DTC
CEDIRANIB STK3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KENPAULLONE STK3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
JNJ-7706621 STK3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALSTERPAULLONE STK3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PD-0166285 STK3

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SOTRASTAURIN STK3

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ENTRECTINIB STK3

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GW441756X STK3

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RG-1530 STK3

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOVITINIB STK3

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYC-116 STK3

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TAE-684 STK3

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ILORASERTIB STK3

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PF-00562271 STK3

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CENISERTIB STK3

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

Ensembl: ENSG00000104375
- Version: 101_38
Alternate Names:

STK3 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000104375

Version: 26-July-2011

Alternate Names:

ENSG00000104375 Ensembl Gene Id

STK3 Display Id

SERINE/THREONINE-PROTEIN KINASE 3 (EC 2.7.1.37) (STE20-LIKE KINASE MST2) (MST-2) (MAMMALIAN STE20-LIKE PROTEIN KINASE 2) (SERINE/THREONINE-PROTEIN KINASE KRS-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13188] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

HopkinsGroom: Q13188
- Version: 11-September-2012
Alternate Names:

SERINE/THREONINE-PROTEIN KINASE 3 36KDA SUBUNIT Uniprot Protein Name

STK3_HUMAN Uniprot Id

6788 Entrez Gene Id

Gene Info:

Interpro Type Domain

Uniprot Status Swiss-Prot

Interpro Acc IPR002290

Gene Categories:

KINASE, DRUGGABLE GENOME

Publications:

DTC: STK3

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Kusakabe K et al., 2013, Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125)., J Med Chem

Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.

HingoraniCasas: ENSG00000104375
- Version: 31-May-2017
Alternate Names:

ENSG00000104375 Gene Symbol

STK3 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
IDG: STK3
- Version: 15-July-2019
Alternate Names:

STK3 Gene Symbol

Gene Info:

Gene Categories:

KINASE

Publications:
GO: STK3
- Version: 01-February-2022
Alternate Names:

KRS1 GO Gene Synonym

MST2 GO Gene Synonym

Gene Info:

Gene Categories:

SERINE THREONINE KINASE

Publications:
dGene: STK3
- Version: 27-Jun-2013
Alternate Names:

6788 Gene ID

KRS1 dGene Synonym

MST2 dGene Synonym

Gene Info:

Gene Categories:

KINASE, SERINE THREONINE KINASE

Publications:
Pharos: STK3
- Version: 01-February-2022
Alternate Names:

Serine/threonine-protein kinase 3 Gene Name

Q13188 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:

ENSG00000104375	Ensembl Gene Id
STK3	Display Id
SERINE/THREONINE-PROTEIN KINASE 3 (EC 2.7.1.37) (STE20-LIKE KINASE MST2) (MST-2) (MAMMALIAN STE20-LIKE PROTEIN KINASE 2) (SERINE/THREONINE-PROTEIN KINASE KRS-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13188]	Description

SERINE/THREONINE-PROTEIN KINASE 3 36KDA SUBUNIT	Uniprot Protein Name
STK3_HUMAN	Uniprot Id
6788	Entrez Gene Id

STK3 Gene Record

STK3 6788 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 19035792

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23634759

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
19035792

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
23634759

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

STK3 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000104375 Ensembl Gene Id

STK3 Display Id

SERINE/THREONINE-PROTEIN KINASE 3 (EC 2.7.1.37) (STE20-LIKE KINASE MST2) (MST-2) (MAMMALIAN STE20-LIKE PROTEIN KINASE 2) (SERINE/THREONINE-PROTEIN KINASE KRS-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13188] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME