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SST Gene Record

  • Summary
  • Interactions
  • Claims
  • SST 6750 Druggable Genome

    Alternate Names:

    6750
    SOMATOSTATIN
    SST
    SMST
    182450
    11329
    ENSG00000157005
    OTTHUMG00000156462
    T95479
    SST1

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    HORMONE ACTIVITY
    DRUGGABLE GENOME

    Publications:

    Lung et al., 2000, The cellular oncogene EWS/activating transcription factor 1 is unable to activate adenovirus-borne promoters: implications for cytotoxic prodrug therapy of malignant melanoma of soft parts., Cancer Gene Ther.
    Murao et al., 1995, Suppression of episodic growth hormone secretion in streptozotocin-induced diabetic mice: time-course studies on the hypothalamic pituitary axis., Endocrinology
    Mazzocchi et al., 1985, Effect of somatostatin on the zona glomerulosa of rats treated with angiotensin II or captopril: stereology and plasma hormone concentrations., J. Steroid Biochem.
    Kanatsuka et al., 1983, Somatostatin and insulin secretion from pancreatic islets: studies on the effect of high K+, 9-aminoacridine and valinomycin., Metab. Clin. Exp.
    Berrettini et al., 1987, CSF neuropeptides in euthymic bipolar patients and controls., Br J Psychiatry
    Ahrén et al., 1989, Cysteamine and the endocrine pancreas: immunocytochemical, immunochemical, and functional aspects., Cell Tissue Res.
    Terry et al., 1985, Cysteamine effects on monoamines, dopamine-beta-hydroxylase and the hypothalamic-pituitary axis., Neuroendocrinology
    McIntosh et al., 1988, Cysteamine-induced reduction in gastrointestinal somatostatin: evidence for a region-specific loss in immunoreactivity., Regul. Pept.
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    McIntosh et al., 1984, Effect of cysteamine on secretion of gastrin and somatostatin from the rat stomach., Gastroenterology
    Martin-Iverson et al., 1986, The effects of cysteamine on dopamine-mediated behaviors: evidence for dopamine-somatostatin interactions in the striatum., Pharmacol. Biochem. Behav.
  • CYSTEAMINE   SST

    Interaction Score: 17.67

    Interaction Types & Directionality:
    binder

    Interaction Info:

    PMIDs:
    2653642 4080089 2901134 11752352 6142843


    Sources:
    TTD

  • VALINOMYCIN   SST

    Interaction Score: 8.83

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6129560


    Sources:
    NCI

  • GANCICLOVIR   SST

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10766345


    Sources:
    NCI

  • AMPHETAMINE   SST

    Interaction Score: 1.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2874568


    Sources:
    NCI

  • CAPTOPRIL   SST

    Interaction Score: 1.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2864479


    Sources:
    NCI

  • LITHIUM   SST

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2888503


    Sources:
    NCI

  • STREPTOZOCIN   SST

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7664670


    Sources:
    NCI

  • Ensembl: ENSG00000157005

    • Version: 101_38

    Alternate Names:
    SST Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: SST

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Lung et al., 2000, The cellular oncogene EWS/activating transcription factor 1 is unable to activate adenovirus-borne promoters: implications for cytotoxic prodrug therapy of malignant melanoma of soft parts., Cancer Gene Ther.
    Murao et al., 1995, Suppression of episodic growth hormone secretion in streptozotocin-induced diabetic mice: time-course studies on the hypothalamic pituitary axis., Endocrinology
    Berrettini et al., 1987, CSF neuropeptides in euthymic bipolar patients and controls., Br J Psychiatry

  • HingoraniCasas: ENSG00000157005

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000157005 Gene Symbol
    SST Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TTD: Somatostatin

    • Version: 2020.06.01

    Alternate Names:
    SST TTD Gene Abbreviation
    T95479 TTD Target ID

    Gene Info:

    Publications:

  • GO: SST

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    HORMONE ACTIVITY

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21