DGIdb - SLC7A4 Gene Record

SLC7A4 6545 Druggable Genome

Alternate Names:

6545
SOLUTE CARRIER FAMILY 7 MEMBER 4
SLC7A4
CAT-4
CAT4
HCAT3
VH
603752
11062
ENSG00000099960
OTTHUMG00000150896
O43246
SOLUTE CARRIER FAMILY 7 (CATIONIC AMINO ACID TRANSPORTER, Y+ SYSTEM), MEMBER 4 [SOURCE:REFSEQ_PEPTIDE;ACC:NP_004164]
NP_004164.1
BE0000052
894
Cationic amino acid transporter 4

Gene Info:

Human Readable Name	DRUGGABLE GENOME
GuideToPharmacology Gene Category Name	SLC7 family
GuideToPharmacology Gene Category ID	169
Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

TRANSPORTER
DRUGGABLE GENOME

Publications:

Rotmann et al., 2007, Activation of classical protein kinase C decreases transport via systems y+ and y+L., Am. J. Physiol., Cell Physiol.
Rotoli et al., 2005, The transport of cationic amino acids in human airway cells: expression of system y+L activity and transepithelial delivery of NOS inhibitors., FASEB J.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

LYSINE SLC7A4

Interaction Score: 16.23

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15746185 17139284 17016423

Sources:
DrugBank
ARGININE SLC7A4

Interaction Score: 5.68

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17329401

Sources:
DrugBank

Ensembl: ENSG00000099960
- Version: 101_38
Alternate Names:

SLC7A4 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000099960

Version: 26-July-2011

Alternate Names:

ENSG00000099960 Ensembl Gene Id

NP_004164.1 Display Id

SOLUTE CARRIER FAMILY 7 (CATIONIC AMINO ACID TRANSPORTER, Y+ SYSTEM), MEMBER 4 [SOURCE:REFSEQ_PEPTIDE;ACC:NP_004164] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

GuideToPharmacology: 6545
- Version: 29-September-2020
Alternate Names:

11062 HUGO Gene ID

11062 HUGO Gene Symbol

solute carrier family 7 member 4 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name SLC7 family

GuideToPharmacology Gene Category ID 169

Gene Categories:

TRANSPORTER

Publications:

DrugBank: BE0000052

Version: 5.1.7

Alternate Names:

SLC7A4 DrugBank Gene Name

O43246 UniProt Accession

6545 Entrez Gene Id

Gene Info:

Publications:

Rotoli et al., 2005, The transport of cationic amino acids in human airway cells: expression of system y+L activity and transepithelial delivery of NOS inhibitors., FASEB J.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Pharos: SLC7A4
- Version: 03-September-2020
Alternate Names:

Cationic amino acid transporter 4 Gene Name

O43246 UniProt ID

Gene Info:

Gene Categories:

TRANSPORTER

Publications: