6335 |
SODIUM VOLTAGE-GATED CHANNEL ALPHA SUBUNIT 9 |
SCN9A |
ETHA |
FEB3B |
GEFSP7 |
HSAN2D |
NE-NA |
NENA |
Nav1.7 |
PN1 |
SFNP |
603415 |
10597 |
ENSG00000169432 |
OTTHUMG00000154044 |
Q15858 |
SCN9A_HUMAN |
Sodium channel protein type IX subunit alpha |
Neuroendocrine sodium channel |
hNE-Na |
Peripheral sodium channel 1 |
Sodium channel protein type 9 subunit alpha |
Voltage-gated sodium channel subunit alpha Nav1.7 |
NP_002968.1 |
SODIUM CHANNEL, VOLTAGE-GATED, TYPE IX, ALPHA [SOURCE:REFSEQ_PEPTIDE;ACC:NP_002968] |
Voltage-gated sodium channel alpha Nav1.7 |
T12119 |
Target Class | Transporters |
Target Subclass | TC:1.A.1.10.5 |
Initial Gene Query | Nav1.7 |
Counted Citations from 1950-2000 | 304 |
Human Readable Name | DRUGGABLE GENOME |
Transmembrane Helix Count | 24 |
Target Subclass | Voltage_gated_ion_channels |
Target Subclass | Channels |
Target Subclass | SodiumChannels |
Target Main Class | Transporters |
Interpro Acc | IPR005821 |
Interpro Type | Domain |
Interpro Name | Ion transport domain |
Human Readable Name | ION CHANNEL |
Interpro Short Name | Ion_trans_dom |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel protein type IX alpha subunit blocker |
inhibitor (inhibitory) |
Trial Name | Ranexa |
Novel drug target | Established target |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | zonisamide,Zonegran, Trerief |
Trial Name | OREX-003, olanzapine plus zonisamide SR |
Novel drug target | Established target |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
Trial Name | ALGRX 3268,Zingo |
blocker (inhibitory) |
modulator |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Trial Name | tetrodotoxin,Tectin, Tetrodin |
Novel drug target | Established target |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
n/a |
Trial Name | Safinamide |
Novel drug target | Established target |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
SCN9A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
NP_002968.1 | Display Id |
ENSG00000169432 | Ensembl Gene Id |
SODIUM CHANNEL, VOLTAGE-GATED, TYPE IX, ALPHA [SOURCE:REFSEQ_PEPTIDE;ACC:NP_002968] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
6335 | Entrez Gene Id |
SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA | Uniprot Protein Name |
Q15858 | Uniprot Accession |
Interpro Acc | IPR005821 |
Interpro Type | Domain |
Human Readable Name | DRUGGABLE GENOME |
ION CHANNEL, DRUGGABLE GENOME |
SCN9A | Gene Symbol |
Q15858 | Uniprot Accession |
ENSG00000169432 | Ensembl Gene Id |
Transmembrane Helix Count | 24 |
Target Subclass | Voltage_gated_ion_channels |
Target Subclass | Channels |
6335 | Entrez Gene ID |
Initial Gene Query | Nav1.7 |
Counted Citations from 1950-2000 | 304 |
ION CHANNEL |
SCN9A | Gene Symbol |
Target Class | Transporters |
Target Subclass | TC:1.A.1.10.5 |
NENA | GENE_SYMBOL |
SCN9A | GENE_SYMBOL |
Sodium channel protein type 9 subunit alpha | UNIPROT |
ENSG00000169432 | Gene Symbol |
SCN9A | Ensembl Id |
DRUGGABLE GENOME |
SCN9A | TTD Gene Abbreviation |
T12119 | TTD Target ID |
Sodium channel protein type 9 subunit alpha | Gene Name |
Q15858 | UniProt ID |
ION CHANNEL |