6331 |
SODIUM VOLTAGE-GATED CHANNEL ALPHA SUBUNIT 5 |
SCN5A |
CDCD2 |
CMD1E |
CMPD2 |
HB1 |
HB2 |
HBBD |
HH1 |
ICCD |
IVF |
LQT3 |
Nav1.5 |
PFHB1 |
SSS1 |
VF1 |
600163 |
10593 |
ENSG00000183873 |
OTTHUMG00000156166 |
PA304 |
Q14524 |
Voltage-gated sodium channel subunit alpha Nav1.5 |
Sodium channel protein type V subunit alpha |
Sodium channel protein cardiac muscle subunit alpha |
Sodium channel protein type 5 subunit alpha |
SCN5A_HUMAN |
SODIUM CHANNEL PROTEIN TYPE V ALPHA SUBUNIT (VOLTAGE-GATED SODIUM CHANNEL ALPHA SUBUNIT NAV1.5) (SODIUM CHANNEL PROTEIN, CARDIAC MUSCLE ALPHA-SUBUNIT) (HH1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14524] |
Voltage-gated sodium channel alpha Nav1.5 |
T39716 |
Initial Gene Query | Nav1.5 |
Counted Citations from 1950-2000 | 1178 |
Transmembrane Helix Count | 22 |
Target Subclass | Channels |
Target Subclass | Voltage_gated_ion_channels |
Target Main Class | Transporters |
Target Subclass | SodiumChannels |
Interpro Acc | IPR005821 |
Interpro Type | Domain |
Interpro Name | Ion transport domain |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
Human Readable Name | ION CHANNEL |
Interpro Short Name | Ion_trans_dom |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Transporters |
Target Subclass | TC:1.A.1.10.3 |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
ION CHANNEL |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
n/a |
Trial Name | licarbazepine , LIC-477 |
Novel drug target | Established target |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | Ranexa |
Novel drug target | Established target |
Mechanism of Interaction | Sodium channel protein type V alpha subunit blocker |
blocker (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Trial Name | Oraqix |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | ALGRX 3268,Zingo |
Novel drug target | Established target |
Trial Name | lidocaine hydrochloride, piroxicam, AK1015,Akten |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
Trial Name | - |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type V alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | riluzole,Rilutek |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | Empatic |
Novel drug target | Established target |
Trial Name | OREX-003, olanzapine plus zonisamide SR |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type V alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Novel drug target | Established target |
n/a |
Trial Name | tetrodotoxin,Tectin, Tetrodin |
Novel drug target | Established target |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type V alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Trial Name | Eslicarbazepine |
Novel drug target | Established target |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
n/a |
Trial Name | - |
Novel drug target | Established target |
blocker (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Trial Name | SPD 417, carbamazepine,Equetro, Carbatrol |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel protein type V alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Trial Name | Safinamide |
Novel drug target | Established target |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
SCN5A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
SCN5A | Gene Symbol |
Target Class | Transporters |
Target Subclass | TC:1.A.1.10.3 |
Q14524 | Uniprot Accession |
ENSG00000183873 | Ensembl Gene Id |
SCN5A | Uniprot Gene Name |
Interpro Acc | IPR005821 |
Interpro Type | Domain |
Interpro Name | Ion transport domain |
ION CHANNEL, DRUGGABLE GENOME |
6331 | Entrez Gene ID |
Initial Gene Query | Nav1.5 |
Counted Citations from 1950-2000 | 1178 |
ION CHANNEL |
SCN5A | Display Id |
ENSG00000183873 | Ensembl Gene Id |
SODIUM CHANNEL PROTEIN TYPE V ALPHA SUBUNIT (VOLTAGE-GATED SODIUM CHANNEL ALPHA SUBUNIT NAV1.5) (SODIUM CHANNEL PROTEIN, CARDIAC MUSCLE ALPHA-SUBUNIT) (HH1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14524] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
6331 | Entrez Gene Id |
Q14524 | Uniprot Accession |
SCN5A_HUMAN | Uniprot Id |
Transmembrane Helix Count | 22 |
Target Subclass | Channels |
Target Subclass | Voltage_gated_ion_channels |
PA304 | PharmGKB ID |
SCN5A | GENE_SYMBOL |
Sodium channel protein type 5 subunit alpha | UNIPROT |
HH1 | UNIPROT |
ENSG00000183873 | Gene Symbol |
SCN5A | Ensembl Id |
DRUGGABLE GENOME |
SCN5A | TTD Gene Abbreviation |
T39716 | TTD Target ID |
Sodium channel protein type 5 subunit alpha | Gene Name |
Q14524 | UniProt ID |
ION CHANNEL |
CELL SURFACE |