RPS6KA5 Gene Record

  • RPS6KA5 9252 Druggable Genome

    Alternate Names:

    9252
    RIBOSOMAL PROTEIN S6 KINASE A5
    RPS6KA5
    MSK1
    MSPK1
    RLPK
    603607
    10434
    ENSG00000100784
    OTTHUMG00000171055
    O75582
    KS6A5_HUMAN
    RIBOSOMAL PROTEIN S6 KINASE ALPHA-5
    RIBOSOMAL PROTEIN S6 KINASE ALPHA 5 (EC 2.7.1.37) (NUCLEAR MITOGEN-AND STRESS-ACTIVATED PROTEIN KINASE-1) (90 KDA RIBOSOMAL PROTEIN S6 KINASE 5) (RSK-LIKE PROTEIN KINASE) (RLSK). [SOURCE:UNIPROT/SWISSPROT;ACC:O75582]
    RSK5
    T50224

    Gene Info:

    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Interpro Type Domain
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    TRANSCRIPTION FACTOR

    Publications:

  • GW843682X   RPS6KA5

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HESPERADIN   RPS6KA5

    Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

  • GSK-269962A   RPS6KA5

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   RPS6KA5

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LINIFANIB   RPS6KA5

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOVITINIB   RPS6KA5

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   RPS6KA5

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000100784

    • Version: 101_38

    Alternate Names:
    RPS6KA5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: O75582

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000100784 Ensembl Gene Id
    RPS6KA5 Uniprot Gene Name
    9252 Entrez Gene Id

    Gene Info:
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000100784

    • Version: 26-July-2011

    Alternate Names:
    KS6A5_HUMAN Display Id
    ENSG00000100784 Ensembl Gene Id
    RIBOSOMAL PROTEIN S6 KINASE ALPHA 5 (EC 2.7.1.37) (NUCLEAR MITOGEN-AND STRESS-ACTIVATED PROTEIN KINASE-1) (90 KDA RIBOSOMAL PROTEIN S6 KINASE 5) (RSK-LIKE PROTEIN KINASE) (RLSK). [SOURCE:UNIPROT/SWISSPROT;ACC:O75582] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • DTC: RPS6KA5

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.

  • HingoraniCasas: ENSG00000100784

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000100784 Gene Symbol
    RPS6KA5 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: RPS6KA5

    • Version: 01-February-2022

    Alternate Names:
    MSK1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: RPS6KA5

    • Version: 27-Jun-2013

    Alternate Names:
    9252 Gene ID
    MSK1 dGene Synonym
    MSPK1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Ribosomal protein S6 kinase alpha-5

    • Version: 2020.06.01

    Alternate Names:
    RSK5 TTD Gene Abbreviation
    T50224 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: RPS6KA5

    • Version: 01-February-2022

    Alternate Names:
    Ribosomal protein S6 kinase alpha-5 Gene Name
    O75582 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications: