DGIdb - RIPK2 Gene Record

RIPK2 8767 Druggable Genome

Alternate Names:

8767
RECEPTOR INTERACTING SERINE/THREONINE KINASE 2
RIPK2
CARD3
CARDIAK
CCK
GIG30
RICK
RIP2
603455
10020
ENSG00000104312
OTTHUMG00000163809
O43353
RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 (EC 2.7.1.37) (RIP-LIKE INTERACTING CLARP KINASE) (RECEPTOR-INTERACTING PROTEIN 2) (RIP-2) (CARD-CONTAINING INTERLEUKIN-1 BETA CONVERTING ENZYME ASSOCIATED KINASE) (CARD-CONTAINING IL-1 BETA ICE-KINAS
UNQ277/PRO314/PRO34092
Receptor-interacting serine/threonine-protein kinase 2

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Gene Biotype	PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

KINASE
SERINE THREONINE KINASE
DRUGGABLE GENOME

Publications:

Degterev A et al., 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins., Nat Chem Biol
Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem

PD-169316 RIPK2

Interaction Score: 5.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18408713

Sources:
DTC
SB-202190 RIPK2

Interaction Score: 1.77

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22951114

Sources:
DTC

Ensembl: ENSG00000104312
- Version: 101_38
Alternate Names:

RIPK2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000104312

Version: 26-July-2011

Alternate Names:

ENSG00000104312 Ensembl Gene Id

RIPK2 Display Id

RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 (EC 2.7.1.37) (RIP-LIKE INTERACTING CLARP KINASE) (RECEPTOR-INTERACTING PROTEIN 2) (RIP-2) (CARD-CONTAINING INTERLEUKIN-1 BETA CONVERTING ENZYME ASSOCIATED KINASE) (CARD-CONTAINING IL-1 BETA ICE-KINAS Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

DTC: RIPK2

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Degterev A et al., 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins., Nat Chem Biol

Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem

HingoraniCasas: ENSG00000104312
- Version: 31-May-2017
Alternate Names:

ENSG00000104312 Gene Symbol

RIPK2 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: RIPK2
- Version: 01-February-2022
Alternate Names:

CARDIAK GO Gene Synonym

RICK GO Gene Synonym

RIP2 GO Gene Synonym

Gene Info:

Gene Categories:

SERINE THREONINE KINASE

Publications:
dGene: RIPK2
- Version: 27-Jun-2013
Alternate Names:

8767 Gene ID

CARD3 dGene Synonym

CARDIAK dGene Synonym

Gene Info:

Gene Categories:

KINASE, SERINE THREONINE KINASE

Publications:
Pharos: RIPK2
- Version: 01-February-2022
Alternate Names:

Receptor-interacting serine/threonine-protein kinase 2 Gene Name

O43353 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:

ENSG00000104312	Ensembl Gene Id
RIPK2	Display Id
RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 (EC 2.7.1.37) (RIP-LIKE INTERACTING CLARP KINASE) (RECEPTOR-INTERACTING PROTEIN 2) (RIP-2) (CARD-CONTAINING INTERLEUKIN-1 BETA CONVERTING ENZYME ASSOCIATED KINASE) (CARD-CONTAINING IL-1 BETA ICE-KINAS	Description

CARDIAK	GO Gene Synonym
RICK	GO Gene Synonym
RIP2	GO Gene Synonym

Receptor-interacting serine/threonine-protein kinase 2	Gene Name
O43353	UniProt ID

RIPK2 Gene Record

RIPK2 8767 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

PD-169316 RIPK2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18408713

Sources: DTC

SB-202190 RIPK2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22951114

Sources: DTC

Ensembl: ENSG00000104312

Alternate Names: RIPK2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000104312

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

DTC: RIPK2

Alternate Names:

Gene Info:

Publications: Degterev A et al., 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins., Nat Chem Biol Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem

HingoraniCasas: ENSG00000104312

Alternate Names: ENSG00000104312 Gene Symbol RIPK2 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

GO: RIPK2

Alternate Names: CARDIAK GO Gene Synonym RICK GO Gene Synonym RIP2 GO Gene Synonym

Gene Info:

Gene Categories: SERINE THREONINE KINASE

Publications:

dGene: RIPK2

Alternate Names: 8767 Gene ID CARD3 dGene Synonym CARDIAK dGene Synonym

Gene Info:

Gene Categories: KINASE, SERINE THREONINE KINASE

Publications:

Pharos: RIPK2

Alternate Names: Receptor-interacting serine/threonine-protein kinase 2 Gene Name O43353 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
18408713

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22951114

Sources:
DTC

Alternate Names:

RIPK2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

Degterev A et al., 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins., Nat Chem Biol

Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem

Alternate Names:

ENSG00000104312 Gene Symbol

RIPK2 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

CARDIAK GO Gene Synonym

RICK GO Gene Synonym

RIP2 GO Gene Synonym

Gene Categories:

SERINE THREONINE KINASE

Alternate Names:

8767 Gene ID

CARD3 dGene Synonym

CARDIAK dGene Synonym

Gene Categories:

KINASE, SERINE THREONINE KINASE

Alternate Names:

Receptor-interacting serine/threonine-protein kinase 2 Gene Name

O43353 UniProt ID

Gene Categories:

KINASE