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RFK Gene Record

  • Summary
  • Interactions
  • Claims
  • RFK 55312

    Alternate Names:

    55312
    RIBOFLAVIN KINASE
    RFK
    RIFK
    613010
    30324
    ENSG00000135002
    OTTHUMG00000020040
    BE0000370
    Q969G6
    PA134916697

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    KINASE
    ENZYME

    Publications:

    Werner et al., 2005, HepG2 cells develop signs of riboflavin deficiency within 4 days of culture in riboflavin-deficient medium., J. Nutr. Biochem.
    Solovieva et al., 2005, The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product., FEMS Microbiol. Lett.
    Bertollo et al., 2006, Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models., Eur. J. Pharmacol.
    Ishchuk et al., [Construction of the flavinogenic yeast Candida famata strains with high riboflavin kinase activity using gene engineering]., Ukr Biokhim Zh (1999)
    Sandoval et al., 2005, An FMN hydrolase is fused to a riboflavin kinase homolog in plants., J. Biol. Chem.
    Hirano et al., 2011, Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin., Int. J. Oncol.
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
  • RIBOFLAVIN   RFK

    Interaction Score: 24.85

    Interaction Types & Directionality:
    ligand

    Interaction Info:

    PMIDs:
    16081269 15668000 16962092 17290783 16183635 21308351


    Sources:
    DrugBank

  • PHOTREXA   RFK

    Interaction Score: 4.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • ESCITALOPRAM   RFK

    Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • CITALOPRAM   RFK

    Interaction Score: 0.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Ensembl: ENSG00000135002

    • Version: 101_38

    Alternate Names:
    RFK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DrugBank: BE0000370

    • Version: 5.1.7

    Alternate Names:
    RFK DrugBank Gene Name
    Q969G6 UniProt Accession
    55312 Entrez Gene Id

    Gene Info:

    Publications:
    Werner et al., 2005, HepG2 cells develop signs of riboflavin deficiency within 4 days of culture in riboflavin-deficient medium., J. Nutr. Biochem.
    Solovieva et al., 2005, The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product., FEMS Microbiol. Lett.
    Bertollo et al., 2006, Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models., Eur. J. Pharmacol.

  • PharmGKB: RFK

    • Version: 18-August-2020

    Alternate Names:
    PA134916697 PharmGKB ID

    Gene Info:

    Publications:

  • Pharos: RFK

    • Version: 03-September-2020

    Alternate Names:
    Riboflavin kinase Gene Name
    Q969G6 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21