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PTGFR 5737 Druggable Genome
Alternate Names:
5737 PROSTAGLANDIN F RECEPTOR PTGFR FP 600563 9600 ENSG00000122420 OTTHUMG00000009644 PGF2-alpha receptor PGF receptor Prostaglandin F2-alpha receptor Prostanoid FP receptor 344 FP receptor P43088 NP_000950 NM_000959 PF2R_HUMAN PA290 BE0000610 PROSTAGLANDIN F2-ALPHA RECEPTOR (PROSTANOID FP RECEPTOR) (PGF RECEPTOR) (PGF2 ALPHA RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P43088] T75797 Gene Info:
Human Readable Name G PROTEIN COUPLED RECEPTOR GuideToPharmacology Gene Category Name Prostanoid receptors GuideToPharmacology Gene Category ID 58 Transmembrane Helix Count 7 Target Subclass GPCR Target Subclass Rhodopsin Target Main Class Receptors Target Class Receptors Human Readable Name DRUGGABLE GENOME Interpro Acc IPR000276 Interpro Short Name 7TM_GPCR_Rhodpsn Interpro Name GPCR, rhodopsin-like, 7TM Uniprot Evidence 2: Evidence at transcript level Interpro Type Family Uniprot Status Swiss-Prot Gene Biotype PROTEIN_CODING Gene Categories: Category Details
G PROTEIN COUPLED RECEPTOR DRUGGABLE GENOME Publications:
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Interaction Score: 46.78
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Novel drug target Established target Trial Name travoprost + timolol,Extravan, Duotrav Mechanism of Interaction Prostanoid FP receptor agonist -
Interaction Score: 18.94
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name sustained release latanoprost Trial Name Nova21027,Catioprost Trial Name latanoprost,Xalatan Fixed Flow Device -
Interaction Score: 16.71
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Prostanoid FP receptor agonist Direct Interaction yes Specific Action of the Ligand Agonist -
Interaction Score: 14.48
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction? True Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Score: 6.68
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Prostanoid FP receptor agonist Direct Interaction yes -
Interaction Score: 3.34
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Prostanoid FP receptor agonist Direct Interaction yes -
Interaction Score: 3.34
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Agonist Endogenous Drug? False Direct Interaction? False -
Interaction Score: 3.34
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction yes Mechanism of Interaction Prostanoid FP receptor agonist -
Interaction Score: 1.11
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Score: 1.11
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Score: 0.67
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Score: 0.51
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? True -
Interaction Score: 0.48
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Interaction Score: 0.42
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Full agonist
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- Version: 101_38
Alternate Names:
PTGFR Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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Alternate Names:
P43088 Uniprot Accession ENSG00000122420 Ensembl Gene Id PF2R_HUMAN Uniprot Id Gene Info:
Transmembrane Helix Count 7 Target Subclass GPCR Target Subclass Rhodopsin Publications:
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- Version: January-2014
Alternate Names:
PTGFR Gene Symbol Gene Info:
Target Class Receptors Target Subclass GPCR Target Subclass Rhodopsin Publications:
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- Version: 11-September-2012
Alternate Names:
P43088 Uniprot Accession PTGFR Uniprot Gene Name ENSG00000122420 Ensembl Gene Id Gene Info:
Interpro Acc IPR000276 Interpro Short Name 7TM_GPCR_Rhodpsn Human Readable Name DRUGGABLE GENOME Gene Categories:
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000122420 Ensembl Gene Id PTGFR Display Id PROSTAGLANDIN F2-ALPHA RECEPTOR (PROSTANOID FP RECEPTOR) (PGF RECEPTOR) (PGF2 ALPHA RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P43088] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
9600 HUGO Gene ID 9600 HUGO Gene Symbol prostaglandin F receptor HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Prostanoid receptors GuideToPharmacology Gene Category ID 58 Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications:
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Alternate Names:
PA290 PharmGKB ID Gene Info:
Publications:
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Alternate Names:
PTGFR DrugBank Gene Name P43088 UniProt Accession 5737 Entrez Gene Id Gene Info:
Publications:
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- Version: chembl_23
Alternate Names:
PTGFR GENE_SYMBOL Prostaglandin F2-alpha receptor UNIPROT Prostanoid FP receptor UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000122420 Gene Symbol PTGFR Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
5737 Gene ID FP dGene Synonym Gene Info:
Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications:
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- Version: 2020.06.01
Alternate Names:
PTGFR TTD Gene Abbreviation T75797 TTD Target ID Gene Info:
Publications: