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PSMD8 Gene Record

  • Summary
  • Interactions
  • Claims
  • PSMD8 5714

    Alternate Names:

    5714
    PROTEASOME 26S SUBUNIT, NON-ATPASE 8
    PSMD8
    HEL-S-91n
    HIP6
    HYPF
    Nin1p
    Rpn12
    S14
    p31
    9566
    ENSG00000099341
    OTTHUMG00000150691
    26S proteasome regulatory subunit S14
    26S proteasome regulatory subunit RPN12
    26S proteasome non-ATPase regulatory subunit 8
    Proteasome
    617844

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem
  • CARFILZOMIB   PSMD8

    Interaction Score: 1.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • BORTEZOMIB   PSMD8

    Interaction Score: 0.69

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • IXAZOMIB CITRATE   PSMD8

    Interaction Score: 0.41

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OPROZOMIB   PSMD8

    Interaction Score: 0.4

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000099341

    • Version: 101_38

    Alternate Names:
    PSMD8 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DTC: PSMD8

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

  • MyCancerGenome: PSMD8

    • Version: 20-Jun-2017

    Alternate Names:
    5714 Entrez Gene Id
    PSMD8 MyCancerGenome Gene Symbol
    Proteasome MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • ChemblInteractions: PSMD8

    • Version: chembl_23

    Alternate Names:
    PSMD8 GENE_SYMBOL
    26S proteasome non-ATPase regulatory subunit 8 UNIPROT
    26S proteasome regulatory subunit RPN12 UNIPROT

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21