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PSMC5 Gene Record

  • Summary
  • Interactions
  • Claims
  • PSMC5 5705

    Alternate Names:

    5705
    PROTEASOME 26S SUBUNIT, ATPASE 5
    PSMC5
    S8
    SUG-1
    SUG1
    TBP10
    TRIP1
    p45
    p45/SUG
    601681
    9552
    ENSG00000087191
    OTTHUMG00000179013
    Proteasome
    Thyroid hormone receptor-interacting protein 1
    26S protease regulatory subunit 8
    26S proteasome AAA-ATPase subunit RPT6
    Proteasome 26S subunit ATPase 5
    Proteasome subunit p45
    RPT6

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    PROTEASE
    TRANSCRIPTION FACTOR BINDING

    Publications:

    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem
  • IXAZOMIB   PSMC5

    Interaction Score: 6.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • CARFILZOMIB   PSMC5

    Interaction Score: 0.87

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • BORTEZOMIB   PSMC5

    Interaction Score: 0.55

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • IXAZOMIB CITRATE   PSMC5

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OPROZOMIB   PSMC5

    Interaction Score: 0.32

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000087191

    • Version: 101_38

    Alternate Names:
    PSMC5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DTC: PSMC5

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

  • MyCancerGenome: PSMC5

    • Version: 20-Jun-2017

    Alternate Names:
    5705 Entrez Gene Id
    PSMC5 MyCancerGenome Gene Symbol
    Proteasome MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • ChemblInteractions: SUG1

    • Version: chembl_23

    Alternate Names:
    SUG1 GENE_SYMBOL
    PSMC5 GENE_SYMBOL
    26S protease regulatory subunit 8 UNIPROT

    Gene Info:

    Publications:

  • GO: PSMC5

    • Version: 01-February-2022

    Alternate Names:
    SUG1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR BINDING

    Publications:

  • dGene: PSMC5

    • Version: 27-Jun-2013

    Alternate Names:
    5705 Gene ID
    S8 dGene Synonym
    SUG-1 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21