DGIdb - PSMC5 Gene Record

PSMC5 5705

Alternate Names:

5705
PROTEASOME 26S SUBUNIT, ATPASE 5
PSMC5
S8
SUG-1
SUG1
TBP10
TRIP1
p45
p45/SUG
601681
9552
ENSG00000087191
OTTHUMG00000179013
Proteasome
Thyroid hormone receptor-interacting protein 1
26S protease regulatory subunit 8
26S proteasome AAA-ATPase subunit RPT6
Proteasome 26S subunit ATPase 5
Proteasome subunit p45
RPT6

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

PROTEASE
TRANSCRIPTION FACTOR BINDING

Publications:

Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

IXAZOMIB PSMC5

Interaction Score: 6.18

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
CARFILZOMIB PSMC5

Interaction Score: 0.87

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions
BORTEZOMIB PSMC5

Interaction Score: 0.55

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions
IXAZOMIB CITRATE PSMC5

Interaction Score: 0.33

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
OPROZOMIB PSMC5

Interaction Score: 0.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Ensembl: ENSG00000087191
- Version: 101_38
Alternate Names:

PSMC5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DTC: PSMC5

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

MyCancerGenome: PSMC5
- Version: 20-Jun-2017
Alternate Names:

5705 Entrez Gene Id

PSMC5 MyCancerGenome Gene Symbol

Proteasome MyCancerGenome Reported Gene Name

Gene Info:

Publications:
ChemblInteractions: SUG1
- Version: chembl_23
Alternate Names:

SUG1 GENE_SYMBOL

PSMC5 GENE_SYMBOL

26S protease regulatory subunit 8 UNIPROT

Gene Info:

Publications:
GO: PSMC5
- Version: 01-February-2022
Alternate Names:

SUG1 GO Gene Synonym

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR BINDING

Publications:
dGene: PSMC5
- Version: 27-Jun-2013
Alternate Names:

5705 Gene ID

S8 dGene Synonym

SUG-1 dGene Synonym

Gene Info:

Gene Categories:

PROTEASE

Publications:

Mechanism of Interaction	26S proteosome inhibitor
Direct Interaction	yes

5705	Entrez Gene Id
PSMC5	MyCancerGenome Gene Symbol
Proteasome	MyCancerGenome Reported Gene Name

SUG1	GENE_SYMBOL
PSMC5	GENE_SYMBOL
26S protease regulatory subunit 8	UNIPROT

5705	Gene ID
S8	dGene Synonym
SUG-1	dGene Synonym

PSMC5 Gene Record

PSMC5 5705

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

IXAZOMIB PSMC5

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

CARFILZOMIB PSMC5

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: 24524217

Sources: DTC MyCancerGenome ChemblInteractions

BORTEZOMIB PSMC5

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: 24524217

Sources: DTC MyCancerGenome ChemblInteractions

IXAZOMIB CITRATE PSMC5

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

OPROZOMIB PSMC5

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Ensembl: ENSG00000087191

Alternate Names: PSMC5 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DTC: PSMC5

Alternate Names:

Gene Info:

Publications: Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

MyCancerGenome: PSMC5

Alternate Names: 5705 Entrez Gene Id PSMC5 MyCancerGenome Gene Symbol Proteasome MyCancerGenome Reported Gene Name

Gene Info:

Publications:

ChemblInteractions: SUG1

Alternate Names: SUG1 GENE_SYMBOL PSMC5 GENE_SYMBOL 26S protease regulatory subunit 8 UNIPROT

Gene Info:

Publications:

GO: PSMC5

Alternate Names: SUG1 GO Gene Synonym

Gene Info:

Gene Categories: TRANSCRIPTION FACTOR BINDING

Publications:

dGene: PSMC5

Alternate Names: 5705 Gene ID S8 dGene Synonym SUG-1 dGene Synonym

Gene Info:

Gene Categories: PROTEASE

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Alternate Names:

PSMC5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

Alternate Names:

5705 Entrez Gene Id

PSMC5 MyCancerGenome Gene Symbol

Proteasome MyCancerGenome Reported Gene Name

Alternate Names:

SUG1 GENE_SYMBOL

PSMC5 GENE_SYMBOL

26S protease regulatory subunit 8 UNIPROT

Alternate Names:

SUG1 GO Gene Synonym

Gene Categories:

TRANSCRIPTION FACTOR BINDING

Alternate Names:

5705 Gene ID

S8 dGene Synonym

SUG-1 dGene Synonym

Gene Categories:

PROTEASE