• Interaction Score: 7.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18801655


    Sources:
    DTC

  • Interaction Score: 2.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24321833


    Sources:
    DTC

  • Interaction Score: 1.78

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Inhibition of proteolytic activity measured in MOLT-4 (human T cell leukemia) cell lysate using the ProCISE ELISA.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.87

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes
    Novel drug target Established target

  • Interaction Score: 0.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes
    Trial Name Velcade

  • Interaction Score: 0.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name MLN-9708
    Novel drug target Established target
    Mechanism of Interaction 26S proteosome inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.36

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name ONX 0912
    Novel drug target Established target
    Mechanism of Interaction 26S proteosome inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.36

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 20S Proteasome inhibitor
    Direct Interaction yes

    PMIDs:
    None found