DGIdb - PSMA7 Gene Record

PSMA7 5688 Druggable Genome

Alternate Names:

5688
PROTEASOME SUBUNIT ALPHA 7
PSMA7
C6
HEL-S-276
HSPC
RC6-1
XAPC7
606607
9536
ENSG00000101182
OTTHUMG00000032895
O14818
Proteasome subunit XAPC7
Proteasome subunit alpha type-7
Proteasome subunit RC6-1
BE0003916
Proteasome

Gene Info:

Gene Biotype	PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

PROTEASE
DRUGGABLE GENOME

Publications:

Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

CHEMBL304784 PSMA7

Interaction Score: 18.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CARFILZOMIB PSMA7

Interaction Score: 0.66

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions
MARIZOMIB PSMA7

Interaction Score: 0.47

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 20S Proteasome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
BORTEZOMIB PSMA7

Interaction Score: 0.42

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions
IXAZOMIB CITRATE PSMA7

Interaction Score: 0.25

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
OPROZOMIB PSMA7

Interaction Score: 0.24

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Ensembl: ENSG00000101182
- Version: 101_38
Alternate Names:

PSMA7 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
DrugBank: BE0003916
- Version: 5.1.7
Alternate Names:

PSMA7 DrugBank Gene Name

O14818 UniProt Accession

5688 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

DTC: PSMA7

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

HingoraniCasas: ENSG00000101182
- Version: 31-May-2017
Alternate Names:

ENSG00000101182 Gene Symbol

PSMA7 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
MyCancerGenome: PSMA7
- Version: 20-Jun-2017
Alternate Names:

5688 Entrez Gene Id

PSMA7 MyCancerGenome Gene Symbol

Proteasome MyCancerGenome Reported Gene Name

Gene Info:

Publications:
ChemblInteractions: HSPC
- Version: chembl_23
Alternate Names:

HSPC GENE_SYMBOL

PSMA7 GENE_SYMBOL

Proteasome subunit alpha type-7 UNIPROT

Gene Info:

Publications:
dGene: PSMA7
- Version: 27-Jun-2013
Alternate Names:

5688 Gene ID

C6 dGene Synonym

HSPC dGene Synonym

Gene Info:

Gene Categories:

PROTEASE

Publications:

Mechanism of Interaction	26S proteosome inhibitor
Direct Interaction	yes

Mechanism of Interaction	20S Proteasome inhibitor
Direct Interaction	yes

PSMA7	DrugBank Gene Name
O14818	UniProt Accession
5688	Entrez Gene Id

HSPC	GENE_SYMBOL
PSMA7	GENE_SYMBOL
Proteasome subunit alpha type-7	UNIPROT

5688	Gene ID
C6	dGene Synonym
HSPC	dGene Synonym

PSMA7 Gene Record

PSMA7 5688 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

CHEMBL304784 PSMA7

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

CARFILZOMIB PSMA7

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: 24524217

Sources: DTC MyCancerGenome ChemblInteractions

MARIZOMIB PSMA7

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 20S Proteasome inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

BORTEZOMIB PSMA7

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: 24524217

Sources: DTC MyCancerGenome ChemblInteractions

IXAZOMIB CITRATE PSMA7

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

OPROZOMIB PSMA7

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction 26S proteosome inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Ensembl: ENSG00000101182

Alternate Names: PSMA7 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0003916

Alternate Names: PSMA7 DrugBank Gene Name O14818 UniProt Accession 5688 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

DTC: PSMA7

Alternate Names:

Gene Info:

Publications: Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

HingoraniCasas: ENSG00000101182

Alternate Names: ENSG00000101182 Gene Symbol PSMA7 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

MyCancerGenome: PSMA7

Alternate Names: 5688 Entrez Gene Id PSMA7 MyCancerGenome Gene Symbol Proteasome MyCancerGenome Reported Gene Name

Gene Info:

Publications:

ChemblInteractions: HSPC

Alternate Names: HSPC GENE_SYMBOL PSMA7 GENE_SYMBOL Proteasome subunit alpha type-7 UNIPROT

Gene Info:

Publications:

dGene: PSMA7

Alternate Names: 5688 Gene ID C6 dGene Synonym HSPC dGene Synonym

Gene Info:

Gene Categories: PROTEASE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 20S Proteasome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
24524217

Sources:
DTC MyCancerGenome ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction 26S proteosome inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Alternate Names:

PSMA7 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PSMA7 DrugBank Gene Name

O14818 UniProt Accession

5688 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Publications:

Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

Alternate Names:

ENSG00000101182 Gene Symbol

PSMA7 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

5688 Entrez Gene Id

PSMA7 MyCancerGenome Gene Symbol

Proteasome MyCancerGenome Reported Gene Name

Alternate Names:

HSPC GENE_SYMBOL

PSMA7 GENE_SYMBOL

Proteasome subunit alpha type-7 UNIPROT

Alternate Names:

5688 Gene ID

C6 dGene Synonym

HSPC dGene Synonym

Gene Categories:

PROTEASE