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PSMA7 Gene Record

  • Summary
  • Interactions
  • Claims
  • PSMA7 5688 Druggable Genome

    Alternate Names:

    5688
    PROTEASOME SUBUNIT ALPHA 7
    PSMA7
    C6
    HEL-S-276
    HSPC
    RC6-1
    XAPC7
    606607
    9536
    ENSG00000101182
    OTTHUMG00000032895
    O14818
    Proteasome subunit XAPC7
    Proteasome subunit alpha type-7
    Proteasome subunit RC6-1
    BE0003916
    Proteasome

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME

    Publications:

    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
  • CHEMBL304784   PSMA7

    Interaction Score: 18.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CARFILZOMIB   PSMA7

    Interaction Score: 0.66

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • MARIZOMIB   PSMA7

    Interaction Score: 0.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 20S Proteasome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • BORTEZOMIB   PSMA7

    Interaction Score: 0.42

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • IXAZOMIB CITRATE   PSMA7

    Interaction Score: 0.25

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OPROZOMIB   PSMA7

    Interaction Score: 0.24

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000101182

    • Version: 101_38

    Alternate Names:
    PSMA7 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DrugBank: BE0003916

    • Version: 5.1.7

    Alternate Names:
    PSMA7 DrugBank Gene Name
    O14818 UniProt Accession
    5688 Entrez Gene Id

    Gene Info:

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

  • DTC: PSMA7

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

  • HingoraniCasas: ENSG00000101182

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000101182 Gene Symbol
    PSMA7 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • MyCancerGenome: PSMA7

    • Version: 20-Jun-2017

    Alternate Names:
    5688 Entrez Gene Id
    PSMA7 MyCancerGenome Gene Symbol
    Proteasome MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • ChemblInteractions: HSPC

    • Version: chembl_23

    Alternate Names:
    HSPC GENE_SYMBOL
    PSMA7 GENE_SYMBOL
    Proteasome subunit alpha type-7 UNIPROT

    Gene Info:

    Publications:

  • dGene: PSMA7

    • Version: 27-Jun-2013

    Alternate Names:
    5688 Gene ID
    C6 dGene Synonym
    HSPC dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21