PRKX Gene Record

  • PRKX 5613 Druggable Genome

    Alternate Names:

    5613
    PROTEIN KINASE, X-LINKED
    PRKX
    PKX1
    300083
    9441
    ENSG00000183943
    OTTHUMG00000021087
    2175
    P51817
    NP_005035
    NM_005044
    PRKX_HUMAN
    SERINE/THREONINE-PROTEIN KINASE PRKX (EC 2.7.1.37) (PROTEIN KINASE PKX1). [SOURCE:UNIPROT/SWISSPROT;ACC:P51817]
    CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX
    protein kinase X-linked

    Gene Info:

    GuideToPharmacology Gene Category ID 284
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Acc IPR002290
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Human Readable Name KINASE
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Protein kinase A (PKA) family
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • HYDROXYFASUDIL   PRKX

    Interaction Score: 9.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22257127


    Sources:
    DTC

  • Y-27632   PRKX

    Interaction Score: 3.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22257127


    Sources:
    DTC

  • FASUDIL   PRKX

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22257127


    Sources:
    DTC

  • GSK-690693   PRKX

    Interaction Score: 0.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • GW843682X   PRKX

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1997335   PRKX

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   PRKX

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GSK-269962A   PRKX

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PALBOCICLIB   PRKX

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PD-0166285   PRKX

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   PRKX

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOVITINIB   PRKX

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   PRKX

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   PRKX

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000183943

    • Version: 101_38

    Alternate Names:
    PRKX Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P51817

    • Version: 11-September-2012

    Alternate Names:
    PRKX Uniprot Gene Name
    ENSG00000183943 Ensembl Gene Id
    P51817 Uniprot Accession

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000183943

    • Version: 26-July-2011

    Alternate Names:
    SERINE/THREONINE-PROTEIN KINASE PRKX (EC 2.7.1.37) (PROTEIN KINASE PKX1). [SOURCE:UNIPROT/SWISSPROT;ACC:P51817] Description
    PRKX Display Id
    ENSG00000183943 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GuideToPharmacology: 5613

    • Version: 29-September-2020

    Alternate Names:
    9441 HUGO Gene ID
    9441 HUGO Gene Symbol
    protein kinase X-linked HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Protein kinase A (PKA) family
    GuideToPharmacology Gene Category ID 284

    Gene Categories:
    ENZYME

    Publications:

  • DTC: PRKX

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Jester BW et al., 2012, Testing the promiscuity of commercial kinase inhibitors against the AGC kinase group using a split-luciferase screen., J Med Chem

  • HingoraniCasas: ENSG00000183943

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000183943 Gene Symbol
    PRKX Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: PRKX

    • Version: 19.3

    Alternate Names:
    ENSG00000183943 Ensembl Gene ID
    PKX1 Human Protein Atlas Gene Synonym
    Protein kinase, X-linked Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • dGene: PRKX

    • Version: 27-Jun-2013

    Alternate Names:
    5613 Gene ID
    PKX1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • Pharos: PRKX

    • Version: 01-May-2021

    Alternate Names:
    cAMP-dependent protein kinase catalytic subunit PRKX Gene Name
    P51817 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: