5581 |
PROTEIN KINASE C EPSILON |
PRKCE |
PKCE |
nPKC-epsilon |
176975 |
9401 |
ENSG00000171132 |
OTTHUMG00000128817 |
Protein kinase C epsilon type |
Q02156 |
PKC |
PKC-epsilon |
1486 |
BE0003431 |
PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02156] |
NP_005391 |
NM_005400 |
KPCE_HUMAN |
PA33765 |
T00895 |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.13 |
Initial Gene Query | PKC epsilon |
Counted Citations from 1950-2000 | 1023 |
Human Readable Name | DRUGGABLE GENOME |
GuideToPharmacology Gene Category Name | Eta subfamily |
GuideToPharmacology Gene Category ID | 534 |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR002290 |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
Uniprot Status | Swiss-Prot |
Human Readable Name | KINASE |
Interpro Type | Domain |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Gene Biotype | PROTEIN_CODING |
KINASE |
ION CHANNEL |
SERINE THREONINE KINASE |
DRUGGABLE GENOME |
ENZYME |
TRANSCRIPTION FACTOR |
n/a |
Trial Name | KAI-1678 |
Novel drug target | Established target |
n/a |
Trial Name | Bryostatin |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
PRKCE | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
PROTEIN KINASE C EPSILON TYPE | Uniprot Protein Name |
PRKCE | Uniprot Gene Name |
5581 | Entrez Gene Id |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR002290 |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
KINASE, DRUGGABLE GENOME |
5581 | Entrez Gene ID |
Initial Gene Query | PKC epsilon |
Counted Citations from 1950-2000 | 1023 |
KINASE |
PRKCE | Display Id |
PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02156] | Description |
ENSG00000171132 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
PRKCE | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.13 |
9401 | HUGO Gene ID |
9401 | HUGO Gene Symbol |
protein kinase C epsilon | HUGO Gene Name |
GuideToPharmacology Gene Category Name | Eta subfamily |
GuideToPharmacology Gene Category ID | 534 |
ENZYME |
PA33765 | PharmGKB ID |
PRKCE | DrugBank Gene Name |
Q02156 | UniProt Accession |
5581 | Entrez Gene Id |
PRKCE | TTD Gene Abbreviation |
T00895 | TTD Target ID |
nPKC-epsilon | UNIPROT |
PKCE | GENE_SYMBOL |
PRKCE | GENE_SYMBOL |
ENSG00000171132 | Gene Symbol |
PRKCE | Ensembl Id |
DRUGGABLE GENOME |
5581 | Entrez Gene Id |
PRKCE | MyCancerGenome Gene Symbol |
PKC-epsilon | MyCancerGenome Reported Gene Name |
Protein kinase C epsilon type | Gene Name |
Q02156 | UniProt ID |
KINASE, ION CHANNEL, TRANSCRIPTION FACTOR |
PKCE | GO Gene Synonym |
SERINE THREONINE KINASE |
5581 | Gene ID |
PKCE | dGene Synonym |
nPKC-epsilon | dGene Synonym |
KINASE, SERINE THREONINE KINASE |