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PRKCE 5581 Druggable Genome
Alternate Names:
5581 PROTEIN KINASE C EPSILON PRKCE PKCE nPKC-epsilon 176975 9401 ENSG00000171132 OTTHUMG00000128817 Protein kinase C epsilon type Q02156 PKC PKC-epsilon 1486 BE0003431 PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02156] NP_005391 NM_005400 KPCE_HUMAN PA33765 T00895 Gene Info:
Target Class Enzymes Target Subclass EC:2.7.11.13 Initial Gene Query PKC epsilon Counted Citations from 1950-2000 1023 Human Readable Name DRUGGABLE GENOME GuideToPharmacology Gene Category Name Eta subfamily GuideToPharmacology Gene Category ID 534 Uniprot Evidence 1: Evidence at protein level Interpro Acc IPR002290 Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain Uniprot Status Swiss-Prot Human Readable Name KINASE Interpro Type Domain Interpro Short Name Ser/Thr_dual-sp_kinase_dom Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE ION CHANNEL SERINE THREONINE KINASE DRUGGABLE GENOME ENZYME TRANSCRIPTION FACTOR Publications:
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Interaction Types & Directionality:
n/a Interaction Info:
Trial Name KAI-1678 Novel drug target Established target -
Interaction Score: 1.42
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Interaction Score: 1.42
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Interaction Score: 0.39
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Interaction Score: 0.3
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name Bryostatin Novel drug target Established target -
Interaction Score: 0.27
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.25
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
Interaction Score: 0.22
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
-
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Protein kinase C (PKC) inhibitor -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Protein kinase C (PKC) inhibitor -
Interaction Score: 0.16
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Protein kinase C (PKC) inhibitor Direct Interaction yes -
Interaction Score: 0.14
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Protein kinase C (PKC) inhibitor Direct Interaction yes -
Interaction Score: 0.12
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Protein kinase C (PKC) inhibitor Direct Interaction yes Specific Action of the Ligand Inhibition -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
-
Interaction Score: 0.02
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- Version: 101_38
Alternate Names:
PRKCE Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
PROTEIN KINASE C EPSILON TYPE Uniprot Protein Name PRKCE Uniprot Gene Name 5581 Entrez Gene Id Gene Info:
Uniprot Evidence 1: Evidence at protein level Interpro Acc IPR002290 Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: February-2014
Alternate Names:
5581 Entrez Gene ID Gene Info:
Initial Gene Query PKC epsilon Counted Citations from 1950-2000 1023 Gene Categories:
KINASE Publications:
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- Version: 26-July-2011
Alternate Names:
PRKCE Display Id PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02156] Description ENSG00000171132 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
PRKCE Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:2.7.11.13 Publications:
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- Version: 29-September-2020
Alternate Names:
9401 HUGO Gene ID 9401 HUGO Gene Symbol protein kinase C epsilon HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Eta subfamily GuideToPharmacology Gene Category ID 534 Gene Categories:
ENZYME Publications:
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Alternate Names:
PA33765 PharmGKB ID Gene Info:
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Alternate Names:
PRKCE DrugBank Gene Name Q02156 UniProt Accession 5581 Entrez Gene Id Gene Info:
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- Version: 2020.06.01
Alternate Names:
PRKCE TTD Gene Abbreviation T00895 TTD Target ID Gene Info:
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Alternate Names:
Gene Info:
Publications:
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- Version: chembl_23
Alternate Names:
nPKC-epsilon UNIPROT PKCE GENE_SYMBOL PRKCE GENE_SYMBOL Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000171132 Gene Symbol PRKCE Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 20-Jun-2017
Alternate Names:
5581 Entrez Gene Id PRKCE MyCancerGenome Gene Symbol PKC-epsilon MyCancerGenome Reported Gene Name Gene Info:
Publications:
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Alternate Names:
Protein kinase C epsilon type Gene Name Q02156 UniProt ID Gene Info:
Gene Categories:
KINASE, ION CHANNEL, TRANSCRIPTION FACTOR Publications:
-
Alternate Names:
PKCE GO Gene Synonym Gene Info:
Gene Categories:
SERINE THREONINE KINASE Publications:
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Alternate Names:
5581 Gene ID PKCE dGene Synonym nPKC-epsilon dGene Synonym Gene Info:
Gene Categories:
KINASE, SERINE THREONINE KINASE Publications: