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PPT1 Gene Record

  • Summary
  • Interactions
  • Claims
  • PPT1 5538 Druggable Genome

    Alternate Names:

    5538
    PALMITOYL-PROTEIN THIOESTERASE 1
    PPT1
    CLN1
    INCL
    PPT
    600722
    9325
    ENSG00000131238
    OTTHUMG00000004495
    P50897
    T97740

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Potts MB et al., 2015, Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B., Nat Chem Biol
    Aberg et al., 1997, Lamotrigine therapy in infantile neuronal ceroid lipofuscinosis (INCL)., Neuropediatrics
  • PLITIDEPSIN   PPT1

    Interaction Score: 61.83

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25867045


    Sources:
    TTD

  • LAMOTRIGINE   PPT1

    Interaction Score: 2.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9151331


    Sources:
    NCI

  • Ensembl: ENSG00000131238

    • Version: 101_38

    Alternate Names:
    PPT1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TTD: Palmitoyl-protein thioesterase 1

    • Version: 2020.06.01

    Alternate Names:
    PPT1 TTD Gene Abbreviation
    T97740 TTD Target ID

    Gene Info:

    Publications:
    Potts MB et al., 2015, Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B., Nat Chem Biol

  • NCI: PPT1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Aberg et al., 1997, Lamotrigine therapy in infantile neuronal ceroid lipofuscinosis (INCL)., Neuropediatrics

  • HingoraniCasas: ENSG00000131238

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000131238 Gene Symbol
    PPT1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: PPT1

    • Version: 19.3

    Alternate Names:
    ENSG00000131238 Ensembl Gene ID
    CLN1 Human Protein Atlas Gene Synonym
    INCL Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • Pharos: PPT1

    • Version: 01-February-2022

    Alternate Names:
    Palmitoyl-protein thioesterase 1 Gene Name
    P50897 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21