• PIM3 415116 Druggable Genome

    Alternate Names:

    415116
    PIM-3 PROTO-ONCOGENE, SERINE/THREONINE KINASE
    PIM3
    pim-3
    610580
    19310
    ENSG00000198355
    OTTHUMG00000150290
    SERINE/THREONINE-PROTEIN KINASE PIM-3 (EC 2.7.1.37). [SOURCE:UNIPROT/SWISSPROT;ACC:Q86V86]
    2160
    Q86V86
    Serine/threonine-protein kinase pim-3
    PIM3_HUMAN
    NM_001001852
    NP_001001852
    PIM-3 protein kinase
    T16596
    BE0009516

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Target Class Enzymes
    Target Subclass EC:2.7.11.1
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Type Domain
    GuideToPharmacology Gene Category Name PIM family
    GuideToPharmacology Gene Category ID 600
    Gene Biotype PROTEIN_CODING
    (9 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 1.35

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase PIM inhibitor
    Direct Interaction yes
    Trial Name SGI-1776

  • Interaction Score: 1.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase PIM inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase PIM inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Vadimezan
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

    • Version: 101_38

    Alternate Names:
    PIM3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    PIM3 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.1

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PIM3 Uniprot Gene Name
    415116 Entrez Gene Id
    SERINE/THREONINE-PROTEIN KINASE PIM-3 Uniprot Protein Name

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PIM3 Display Id
    ENSG00000198355 Ensembl Gene Id
    SERINE/THREONINE-PROTEIN KINASE PIM-3 (EC 2.7.1.37). [SOURCE:UNIPROT/SWISSPROT;ACC:Q86V86] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    19310 HUGO Gene ID
    19310 HUGO Gene Symbol
    Pim-3 proto-oncogene, serine/threonine kinase HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name PIM family
    GuideToPharmacology Gene Category ID 600

    Gene Categories:
    ENZYME

    Publications:

    • Version: 5.1.7

    Alternate Names:
    PIM3 DrugBank Gene Name
    Q86V86 UniProt Accession
    415116 Entrez Gene Id

    Gene Info:

    • Version: chembl_23

    Alternate Names:
    PIM3 GENE_SYMBOL
    Serine/threonine-protein kinase pim-3 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000198355 Gene Symbol
    PIM3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Serine/threonine-protein kinase pim-3 Gene Name
    Q86V86 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    415116 Gene ID
    pim-3 dGene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    PIM3 TTD Gene Abbreviation
    T16596 TTD Target ID

    Gene Info:

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

  • GO: PIM3

    • Version: 05-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications: