5291 |
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA |
PIK3CB |
P110BETA |
PI3K |
PI3KBETA |
PIK3C1 |
602925 |
8976 |
ENSG00000051382 |
OTTHUMG00000159893 |
PK3CB_HUMAN |
P42338 |
PI3K-beta |
PtdIns-3-kinase subunit p110-beta |
PtdIns-3-kinase subunit beta |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta |
PI3-kinase subunit beta |
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, BETA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT BETA) (PTDINS-3-KINASE P110) (PI3K) (PI3KBETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P42338] |
PI3-kinase beta |
T05031 |
Target Class | Enzymes |
Target Subclass | EC:2.7.1.153 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Name | Phosphatidylinositol 3-/4-kinase, catalytic domain |
Human Readable Name | PHOSPHATIDYLINOSITOL 3 KINASE |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Short Name | PI3/4_kinase_cat_dom |
Interpro Acc | IPR000403 |
Gene Biotype | PROTEIN_CODING |
KINASE |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
PHOSPHATIDYLINOSITOL 3 KINASE |
CLINICALLY ACTIONABLE |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase p110-beta subunit inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase p110-beta subunit inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase p110-beta subunit inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | PI3-kinase class I inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase p110-beta subunit inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | PI3-kinase class I inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | ON 01910.Na,Estybon |
Novel drug target | Novel Target |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | PI3-kinase class I inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase class I inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | PI3-kinase p110-beta subunit inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
PIK3CB | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM | Uniprot Protein Name |
5291 | Entrez Gene Id |
PK3CB_HUMAN | Uniprot Id |
Interpro Name | Phosphatidylinositol 3-/4-kinase, catalytic domain |
Human Readable Name | PHOSPHATIDYLINOSITOL 3 KINASE |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME, PHOSPHATIDYLINOSITOL 3 KINASE |
PIK3CB | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.1.153 |
ENSG00000051382 | Ensembl Gene Id |
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, BETA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT BETA) (PTDINS-3-KINASE P110) (PI3K) (PI3KBETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P42338] | Description |
PIK3CB | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ENSG00000051382 | Gene Symbol |
PIK3CB | Ensembl Id |
DRUGGABLE GENOME |
5291 | Entrez Gene Id |
PIK3CB | MyCancerGenome Gene Symbol |
PI3K | MyCancerGenome Reported Gene Name |
PIK3C1 | GENE_SYMBOL |
PIK3CB | GENE_SYMBOL |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | UNIPROT |
PIK3C1 | GO Gene Synonym |
KINASE |
PIK3CB | Gene Symbol |
CLINICALLY ACTIONABLE |
5291 | Gene ID |
P110BETA | dGene Synonym |
PI3K | dGene Synonym |
KINASE, PHOSPHATIDYLINOSITOL 3 KINASE |
PIK3CB | TTD Gene Abbreviation |
T05031 | TTD Target ID |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Gene Name |
P42338 | UniProt ID |
KINASE, G PROTEIN COUPLED RECEPTOR |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |