DGIdb - PIK3CB Gene Record

PIK3CB 5291 Druggable GenomeClinically Actionable

Alternate Names:

5291
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA
PIK3CB
P110BETA
PI3K
PI3KBETA
PIK3C1
602925
8976
ENSG00000051382
OTTHUMG00000159893
PK3CB_HUMAN
P42338
PI3K-beta
PtdIns-3-kinase subunit p110-beta
PtdIns-3-kinase subunit beta
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta
PI3-kinase subunit beta
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, BETA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT BETA) (PTDINS-3-KINASE P110) (PI3K) (PI3KBETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P42338]
PI3-kinase beta
T05031

Gene Info:

Target Class	Enzymes
Target Subclass	EC:2.7.1.153
Human Readable Name	DRUGGABLE GENOME
Interpro Name	Phosphatidylinositol 3-/4-kinase, catalytic domain
Human Readable Name	PHOSPHATIDYLINOSITOL 3 KINASE
Interpro Type	Domain
Uniprot Evidence	1: Evidence at protein level
Uniprot Status	Swiss-Prot
Interpro Short Name	PI3/4_kinase_cat_dom
Interpro Acc	IPR000403
Gene Biotype	PROTEIN_CODING

(13 More Sources)

Gene Categories: Category Details

KINASE
G PROTEIN COUPLED RECEPTOR
DRUGGABLE GENOME
PHOSPHATIDYLINOSITOL 3 KINASE
CLINICALLY ACTIONABLE

Publications:

Zhuang et al., 2005, Suramin promotes proliferation and scattering of renal epithelial cells., J. Pharmacol. Exp. Ther.
Rosenmüller et al., 2001, Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB., J. Cell. Physiol.
Angeloni et al., 2007, Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress., Biochimie
Theodoropoulou et al., 2006, Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression., Cancer Res.
Tenzer et al., 2001, The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C., Cancer Res.
Iwama et al., 1995, Effect of lovastatin and fluoromevalonate on phosphatidylinositol 3-kinase activity stimulated with PDGF., Clin Exp Pharmacol Physiol Suppl
Ciprés et al., 1999, An IL-2 receptor beta subdomain that controls Bcl-X(L) expression and cell survival., Eur. J. Immunol.
Campbell et al., 2004, The phosphatidylinositol/AKT/atypical PKC pathway is involved in the improved insulin sensitivity by DHEA in muscle and liver of rats in vivo., Life Sci.
Muscarella et al., 2003, Cross-linking of surface IgM in the Burkitt's lymphoma cell line ST486 provides protection against arsenite- and stress-induced apoptosis that is mediated by ERK and phosphoinositide 3-kinase signaling pathways., J. Biol. Chem.
Lee et al., 2006, Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis., Biochim. Biophys. Acta
Rodríguez-Cuenca et al., 2007, Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone., Am. J. Physiol. Endocrinol. Metab.
Yoshioka et al., 2001, Troglitazone enhances glucose uptake induced by alpha-adrenoceptor stimulation via phosphatidylinositol 3-kinase in rat heart., Clin. Exp. Pharmacol. Physiol.
Witters et al., 2004, Combining flavopiridol with various signal transduction inhibitors., Oncol. Rep.
Howells et al., 2005, Inhibition of phosphatidylinositol 3-kinase/protein kinase B signaling is not sufficient to account for indole-3-carbinol-induced apoptosis in some breast and prostate tumor cells., Clin. Cancer Res.
Lova et al., 2003, A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B., J. Biol. Chem.

BAY-1082439 PIK3CB

Interaction Score: 0.59

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
INK-1117 PIK3CB

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
AZD-8186 PIK3CB

Interaction Score: 0.48

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
INDOLE-3-CARBINOL PIK3CB

Interaction Score: 0.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16322316

Sources:
NCI
BIMIRALISIB PIK3CB

Interaction Score: 0.4

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
TTD
SAR-260301 PIK3CB

Interaction Score: 0.3

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
OCTREOTIDE PIK3CB

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16452215

Sources:
NCI
SONOLISIB PIK3CB

Interaction Score: 0.24

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
GSK-2636771 PIK3CB

Interaction Score: 0.22

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions TTD
COPANLISIB PIK3CB

Interaction Score: 0.21

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
PA-799 PIK3CB

Interaction Score: 0.2

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
GSK-1059615 PIK3CB

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
WX-037 PIK3CB

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
ZSTK-474 PIK3CB

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
BUPARLISIB PIK3CB

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions TTD
RECILISIB PIK3CB

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PF-04691502 PIK3CB

Interaction Score: 0.14

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
PWT-33587 PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
ALVOCIDIB PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14767524

Sources:
NCI
SF-1126 PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
RG-7666 PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
RIGOSERTIB PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name ON 01910.Na,Estybon

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
BGT-226 PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PRASTERONE PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15501480

Sources:
NCI
VOXTALISIB PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
OMIPALISIB PIK3CB

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions MyCancerGenomeClinicalTrial
GEDATOLISIB PIK3CB

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
SAMOTOLISIB PIK3CB

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PILARALISIB PIK3CB

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
SURAMIN PIK3CB

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15833899 11473364

Sources:
NCI
APITOLISIB PIK3CB

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
PUQUITINIB PIK3CB

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TASELISIB PIK3CB

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
DS-7423 PIK3CB

Interaction Score: 0.1

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PANULISIB PIK3CB

Interaction Score: 0.1

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
AZD-6482 PIK3CB

Interaction Score: 0.1

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
VS-5584 PIK3CB

Interaction Score: 0.1

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TROGLITAZONE PIK3CB

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11553036

Sources:
NCI
MIDOSTAURIN PIK3CB

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11719451

Sources:
NCI
ALDESLEUKIN PIK3CB

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10229082

Sources:
NCI
DACTOLISIB PIK3CB

Interaction Score: 0.08

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
EPINEPHRINE PIK3CB

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12407113

Sources:
NCI
PICTILISIB PIK3CB

Interaction Score: 0.08

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
ALPELISIB PIK3CB

Interaction Score: 0.07

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome MyCancerGenomeClinicalTrial
FIMEPINOSTAT PIK3CB

Interaction Score: 0.07

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
CAMPTOTHECIN PIK3CB

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12464623

Sources:
NCI
PI-103 PIK3CB

Interaction Score: 0.06

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
LOVASTATIN PIK3CB

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9072409

Sources:
NCI
INFIGRATINIB PIK3CB

Interaction Score: 0.05

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
QUERCETIN PIK3CB

Interaction Score: 0.05

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
17045724

Sources:
MyCancerGenome NCI
PROGESTERONE PIK3CB

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16954335

Sources:
NCI
DOXORUBICIN PIK3CB

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16905201

Sources:
NCI

Ensembl: ENSG00000051382
- Version: 101_38
Alternate Names:

PIK3CB Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P42338
- Version: 11-September-2012
Alternate Names:

PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM Uniprot Protein Name

5291 Entrez Gene Id

PK3CB_HUMAN Uniprot Id

Gene Info:

Interpro Name Phosphatidylinositol 3-/4-kinase, catalytic domain

Human Readable Name PHOSPHATIDYLINOSITOL 3 KINASE

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME, PHOSPHATIDYLINOSITOL 3 KINASE

Publications:
TdgClinicalTrial: P42338
- Version: January-2014
Alternate Names:

PIK3CB Gene Symbol

Gene Info:

Target Class Enzymes

Target Subclass EC:2.7.1.153

Publications:

RussLampel: ENSG00000051382

Version: 26-July-2011

Alternate Names:

ENSG00000051382 Ensembl Gene Id

PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, BETA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT BETA) (PTDINS-3-KINASE P110) (PI3K) (PI3KBETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P42338] Description

PIK3CB Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

NCI: PIK3CB

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Ciprés et al., 1999, An IL-2 receptor beta subdomain that controls Bcl-X(L) expression and cell survival., Eur. J. Immunol.

Campbell et al., 2004, The phosphatidylinositol/AKT/atypical PKC pathway is involved in the improved insulin sensitivity by DHEA in muscle and liver of rats in vivo., Life Sci.

Howells et al., 2005, Inhibition of phosphatidylinositol 3-kinase/protein kinase B signaling is not sufficient to account for indole-3-carbinol-induced apoptosis in some breast and prostate tumor cells., Clin. Cancer Res.

HingoraniCasas: ENSG00000051382
- Version: 31-May-2017
Alternate Names:

ENSG00000051382 Gene Symbol

PIK3CB Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
MyCancerGenome: PIK3CB
- Version: 20-Jun-2017
Alternate Names:

5291 Entrez Gene Id

PIK3CB MyCancerGenome Gene Symbol

PI3K MyCancerGenome Reported Gene Name

Gene Info:

Publications:
ChemblInteractions: PIK3C1
- Version: chembl_23
Alternate Names:

PIK3C1 GENE_SYMBOL

PIK3CB GENE_SYMBOL

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform UNIPROT

Gene Info:

Publications:
GO: PIK3CB
- Version: 01-February-2022
Alternate Names:

PIK3C1 GO Gene Synonym

Gene Info:

Gene Categories:

KINASE

Publications:
Tempus: PIK3CB
- Version: 11-November-2018
Alternate Names:

PIK3CB Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
dGene: PIK3CB
- Version: 27-Jun-2013
Alternate Names:

5291 Gene ID

P110BETA dGene Synonym

PI3K dGene Synonym

Gene Info:

Gene Categories:

KINASE, PHOSPHATIDYLINOSITOL 3 KINASE

Publications:
TTD: PI3-kinase beta
- Version: 2020.06.01
Alternate Names:

PIK3CB TTD Gene Abbreviation

T05031 TTD Target ID

Gene Info:

Publications:
Pharos: PIK3CB
- Version: 01-February-2022
Alternate Names:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Gene Name

P42338 UniProt ID

Gene Info:

Gene Categories:

KINASE, G PROTEIN COUPLED RECEPTOR

Publications:
MskImpact: PIK3CB
- Version: May-2015
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
MyCancerGenomeClinicalTrial: PIK3CB
- Version: 30-February-2014
Alternate Names:

Gene Info:

Publications:
FoundationOneGenes: PIK3CB
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
Oncomine: PIK3CB
- Version: v3
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:

Mechanism of Interaction	PI3-kinase p110-beta subunit inhibitor
Direct Interaction	yes

Direct Interaction	yes
Mechanism of Interaction	PI3-kinase class I inhibitor

PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM	Uniprot Protein Name
5291	Entrez Gene Id
PK3CB_HUMAN	Uniprot Id

ENSG00000051382	Ensembl Gene Id
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, BETA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT BETA) (PTDINS-3-KINASE P110) (PI3K) (PI3KBETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P42338]	Description
PIK3CB	Display Id

PIK3C1	GENE_SYMBOL
PIK3CB	GENE_SYMBOL
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	UNIPROT

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Gene Name
P42338	UniProt ID

PIK3CB Gene Record

PIK3CB 5291 Druggable GenomeClinically Actionable

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16322316

Sources: NCI

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16452215

Sources: NCI

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
16322316

Sources:
NCI

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
16452215

Sources:
NCI

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-beta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
14767524

Sources:
NCI

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a