• Interaction Score: 38.28

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? True
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    10592235


  • Interaction Score: 25.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25815469


    Sources:
    TTD

  • Interaction Score: 6.38

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 10A inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Trial Name CRx-102, prednisolone plus dipyridamole,Synavive

  • Interaction Score: 0.38

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    PDE10A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    PDE10A Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.1.4.17
    Target Subclass 3.1.4.35

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    10846 Entrez Gene Id
    ENSG00000112541 Ensembl Gene Id
    Q9Y233 Uniprot Accession

    Gene Info:
    Target Main Class Enzymes
    Target Subclass 3.1.4.17
    Target Subclass 3.1.4.35

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000112541 Ensembl Gene Id
    CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A (EC 3.1.4.17). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y233] Description
    PDE10A Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    10846 Entrez Gene Id
    PDE10_HUMAN Uniprot Id
    Q9Y233 Uniprot Accession

    Gene Info:
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002073

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    8772 HUGO Gene ID
    8772 HUGO Gene Symbol
    phosphodiesterase 10A HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)
    GuideToPharmacology Gene Category ID 260

    Gene Categories:
    ENZYME

    Publications:

    • Version: 2020.06.01
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000112541 Gene Symbol
    PDE10A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PDE10A GENE_SYMBOL
    cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A UNIPROT

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Gene Name
    Q9Y233 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications: