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PADI4 Gene Record

  • Summary
  • Interactions
  • Claims
  • PADI4 23569

    Alternate Names:

    23569
    PEPTIDYL ARGININE DEIMINASE 4
    PADI4
    PAD
    PAD4
    PADI5
    PDI4
    PDI5
    605347
    18368
    ENSG00000159339
    OTTHUMG00000002371
    Q9UM07
    PA32903
    Protein-arginine deiminase type-4

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Causey CP et al., 2011, The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors., J Med Chem
    Dreyton CJ et al., 2014, Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation., Bioorg Med Chem
  • CHEMBL1910971   PADI4

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21882827


    Sources:
    DTC

  • CHEMBL1910970   PADI4

    Interaction Score: 10.3

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    21882827


    Sources:
    DTC

  • STREPTONIGRIN   PADI4

    Interaction Score: 2.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24440480


    Sources:
    DTC

  • Ensembl: ENSG00000159339

    • Version: 101_38

    Alternate Names:
    PADI4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: PADI4

    • Version: 18-August-2020

    Alternate Names:
    PA32903 PharmGKB ID

    Gene Info:

    Publications:
    Ala-Mutka EM et al., 2018, Effect of hydrochlorothiazide on serum uric acid concentration: a genome-wide association study., Pharmacogenomics

  • DTC: PADI4

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Causey CP et al., 2011, The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors., J Med Chem
    Dreyton CJ et al., 2014, Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation., Bioorg Med Chem

  • HumanProteinAtlas: PADI4

    • Version: 19.3

    Alternate Names:
    PADI5 Human Protein Atlas Gene Synonym
    ENSG00000159339 Ensembl Gene ID
    PAD Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • Pharos: PADI4

    • Version: 01-February-2022

    Alternate Names:
    Protein-arginine deiminase type-4 Gene Name
    Q9UM07 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21