DGIdb - NTF3 Gene Record

NTF3 4908 Druggable Genome

Alternate Names:

4908
NEUROTROPHIN 3
NTF3
HDNF
NGF-2
NGF2
NT-3
NT3
162660
8023
ENSG00000185652
OTTHUMG00000168649

Gene Info:

Gene Biotype	PROTEIN_CODING

(0 More Sources)

Gene Categories: Category Details

GROWTH FACTOR
DRUGGABLE GENOME

Publications:

Lindholm et al., 1994, Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus., Int. J. Dev. Neurosci.
Ceccatelli et al., 1991, Expanded distribution of mRNA for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the rat brain after colchicine treatment., Proc. Natl. Acad. Sci. U.S.A.
Musselman et al., Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model., Reprod. Toxicol.
Ursø et al., 1999, Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like growth factor receptor in 3T3-L1 adipocytes., J. Biol. Chem.
Koh et al., 1995, Potentiated necrosis of cultured cortical neurons by neurotrophins., Science
Shin-young et al., 2007, Nicotine inhibits bFGF-induced neurite outgrowth through suppression of NO synthesis in H19-7 cells., Neurochem. Res.
He et al., 2000, Intracellular Ca(2+) and Ca(2+)/calmodulin-dependent kinase II mediate acute potentiation of neurotransmitter release by neurotrophin-3., J. Cell Biol.
Malcangio et al., 2000, Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord., Eur. J. Neurosci.
Malcangio et al., 1997, Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord., J. Neurosci.
Park et al., 2006, ERK-mediated production of neurotrophic factors by astrocytes promotes neuronal stem cell differentiation by erythropoietin., Biochem. Biophys. Res. Commun.
Good et al., 2001, Neurotrophin-3 inhibits HCO absorption via a cAMP-dependent pathway in renal thick ascending limb., Am. J. Physiol., Cell Physiol.
Leingärtner et al., 1994, Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons., J. Biol. Chem.
Sano, 2001, Radicicol and geldanamycin prevent neurotoxic effects of anti-cancer drugs on cultured embryonic sensory neurons., Neuropharmacology
Vizzard, 2000, Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction., Exp. Neurol.
Iwata et al., 1996, Neurotrophin-3 increases the DNA-binding activities of several transcription factors in a mouse osteoblastic cell line., Biochim. Biophys. Acta
Becker et al., 2008, Expression of mRNA of neurotrophic factors and their receptors are significantly altered after subchronic ketamine treatment., Med Chem

NALOXONE NTF3

Interaction Score: 0.7

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9334418

Sources:
NCI
PILOCARPINE NTF3

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7747601

Sources:
NCI
INOSITOL NTF3

Interaction Score: 0.55

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10811820

Sources:
NCI
CAPSAICIN NTF3

Interaction Score: 0.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10651868

Sources:
NCI
NIMODIPINE NTF3

Interaction Score: 0.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7725105

Sources:
NCI
ALTEPLASE NTF3

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8630334

Sources:
NCI
EPOETIN ALFA NTF3

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16337149

Sources:
NCI
LIOTHYRONINE SODIUM NTF3

Interaction Score: 0.26

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8288635

Sources:
NCI
PHENYTOIN NTF3

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7841657

Sources:
NCI
COLCHICINE NTF3

Interaction Score: 0.17

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1946455

Sources:
NCI
NICOTINE NTF3

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17268847

Sources:
NCI
GENISTEIN NTF3

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11698238

Sources:
NCI
INSULIN NTF3

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10521479

Sources:
NCI
RISPERIDONE NTF3

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18473918

Sources:
NCI
VINCRISTINE NTF3

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11378165

Sources:
NCI
CYCLOPHOSPHAMIDE NTF3

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10683293

Sources:
NCI

Ensembl: ENSG00000185652
- Version: 101_38
Alternate Names:

NTF3 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

NCI: NTF3

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Ceccatelli et al., 1991, Expanded distribution of mRNA for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the rat brain after colchicine treatment., Proc. Natl. Acad. Sci. U.S.A.

Koh et al., 1995, Potentiated necrosis of cultured cortical neurons by neurotrophins., Science

Park et al., 2006, ERK-mediated production of neurotrophic factors by astrocytes promotes neuronal stem cell differentiation by erythropoietin., Biochem. Biophys. Res. Commun.

HingoraniCasas: ENSG00000185652
- Version: 31-May-2017
Alternate Names:

ENSG00000185652 Gene Symbol

NTF3 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: NTF3
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

GROWTH FACTOR

Publications:

NTF3 Gene Record

NTF3 4908 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9334418

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7747601

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10811820

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10651868

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7725105

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8630334

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16337149

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8288635

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7841657

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1946455

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17268847

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11698238

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10521479

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18473918

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11378165

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10683293

Sources: NCI

Ensembl: ENSG00000185652

Alternate Names: NTF3 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

NCI: NTF3

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000185652

Alternate Names: ENSG00000185652 Gene Symbol NTF3 Ensembl Id

Gene Info:

Interaction Types & Directionality:

n/a

PMIDs:
9334418

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7747601

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10811820

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10651868

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7725105

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8630334

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16337149

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8288635

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7841657

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1946455

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
17268847

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11698238

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10521479

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
18473918

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11378165

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10683293

Sources:
NCI

Alternate Names:

NTF3 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000185652 Gene Symbol

NTF3 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Gene Categories:

GROWTH FACTOR