2908 |
NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1 |
NR3C1 |
GCCR |
GCR |
GCRST |
GR |
GRL |
138040 |
7978 |
ENSG00000113580 |
OTTHUMG00000129677 |
P04150 |
GCR_HUMAN |
GLUCOCORTICOID RECEPTOR |
GLUCOCORTICOID RECEPTOR (GR). [SOURCE:UNIPROT/SWISSPROT;ACC:P04150] |
T40016 |
Target Main Class | Receptors |
Target Subclass | Nuclear receptor |
Human Readable Name | DRUGGABLE GENOME |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
Initial Gene Query | NR3C1 |
Counted Citations from 1950-2000 | 8469 |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR000536 |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | Nucl_hrmn_rcpt_lig-bd_core |
Interpro Type | Domain |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Target Class | Receptors |
Gene Biotype | PROTEIN_CODING |
NUCLEAR HORMONE RECEPTOR |
DRUGGABLE GENOME |
ENZYME |
TRANSCRIPTION FACTOR |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glucocorticoid receptor agonist |
antagonist (inhibitory) |
Mechanism of Interaction | Glucocorticoid receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Trial Name | Dymista, azelastine hydrochloride + fluticasone propionate, MP29-02 |
Novel drug target | Established target |
Trial Name | Fluticasone |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor antagonist |
agonist (activating) |
Trial Name | difluprednate , ST-601,Durezol |
Novel drug target | Established target |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Trial Name | desonide,Desonate HydroGel |
Novel drug target | Established target |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Trial Name | - |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
Trial Name | - |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Trial Name | - |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glucocorticoid receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
Trial Name | betamethasone valerate 0.12% topical foam,BetMetFoam |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Trial Name | fluocinonide,Vanos |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
modulator |
Mechanism of Interaction | Glucocorticoid receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Novel drug target | Established target |
Trial Name | - |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Trial Name | - |
n/a |
Novel drug target | Established target |
Trial Name | Triolex |
agonist (activating) |
modulator |
Mechanism of Interaction | Glucocorticoid receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
antagonist (inhibitory) |
Trial Name | budesonide + formoterol,Symbicort |
Novel drug target | Established target |
Trial Name | budesonide inhalation suspension,Pulmicort Respules |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
Trial Name | - |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
antagonist (inhibitory) |
Trial Name | Mifepristone, RU486 |
Novel drug target | Established target |
Trial Name | mifepristone,Corlux |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
Trial Name | ATL-2502,Colal-Pred |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Glucocorticoid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
Trial Name | triamcinolone acetonide implant,I-vation |
n/a |
Novel drug target | Established target |
Trial Name | clobetasol propionate,Olux Foam |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
Trial Name | CRx-102, prednisolone plus dipyridamole ,Synavive |
agonist (activating) |
Mechanism of Interaction | Glucocorticoid receptor agonist |
Direct Interaction | yes |
n/a |
Trial Name | beclometasone, CHF-1514, / |
Novel drug target | Established target |
Trial Name | beclomethasone dipropionate, BDP HFA,Qvar, Qnaze |
agonist (activating) |
Trial Name | dexamethasone intravitreal implant,Ozurdex, Posurdex |
Novel drug target | Established target |
Trial Name | EGP-437 |
NR3C1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
GCR_HUMAN | Uniprot Id |
NR3C1 | Gene Symbol |
ENSG00000113580 | Ensembl Gene Id |
Target Main Class | Receptors |
Target Subclass | Nuclear receptor |
ENSG00000113580 | Ensembl Gene Id |
GLUCOCORTICOID RECEPTOR (GR). [SOURCE:UNIPROT/SWISSPROT;ACC:P04150] | Description |
NR3C1 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
NR3C1 | Gene Symbol |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
2908 | Entrez Gene ID |
Initial Gene Query | NR3C1 |
Counted Citations from 1950-2000 | 8469 |
NUCLEAR HORMONE RECEPTOR |
GCR_HUMAN | Uniprot Id |
ENSG00000113580 | Ensembl Gene Id |
NR3C1 | Uniprot Gene Name |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Status | Swiss-Prot |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME |
NR3C1 | TTD Gene Abbreviation |
T40016 | TTD Target ID |
ENSG00000113580 | Gene Symbol |
NR3C1 | Ensembl Id |
DRUGGABLE GENOME |
GRL | GENE_SYMBOL |
NR3C1 | GENE_SYMBOL |
Glucocorticoid receptor | UNIPROT |
GRL | GO Gene Synonym |
NUCLEAR HORMONE RECEPTOR |
2908 | Gene ID |
GCCR | dGene Synonym |
GCR | dGene Synonym |
NUCLEAR HORMONE RECEPTOR |
Glucocorticoid receptor | Gene Name |
P04150 | UniProt ID |
ENZYME, TRANSCRIPTION FACTOR |