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NPR1 4881 Druggable Genome
Alternate Names:
4881 NATRIURETIC PEPTIDE RECEPTOR 1 NPR1 ANPRA ANPa GUC2A GUCY2A NPRA 108960 7943 ENSG00000169418 OTTHUMG00000037085 P16066 ATRIAL NATRIURETIC PEPTIDE RECEPTOR 1 ANPRA_HUMAN ANP-A NPR-A ANPR-A Guanylate cyclase A Atrial natriuretic peptide receptor type A GC-A ATRIAL NATRIURETIC PEPTIDE RECEPTOR A ATRIAL NATRIURETIC PEPTIDE RECEPTOR A PRECURSOR (ANP-A) (ANPRA) (GC-A) (GUANYLATE CYCLASE) (EC 4.6.1.2) (NPR-A) (ATRIAL NATRIURETIC PEPTIDE A-TYPE RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P16066] T71230 Gene Info:
Interpro Acc IPR001245 Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Type Family Interpro Type Domain Interpro Acc IPR001170 Interpro Short Name Ntpep_rcpt Human Readable Name DRUGGABLE GENOME Interpro Short Name A/G_cyclase Interpro Name Natriuretic peptide receptor Interpro Acc IPR001054 Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom Human Readable Name KINASE Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase Target Subclass RGC Target Main Class Receptors Transmembrane Helix Count 1 Target Subclass Kinase Target Class Receptors Target Subclass EC:4.6.1.2 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE DRUGGABLE GENOME Publications:
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Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name PL-3994 Novel drug target Established target -
Interaction Score: 12.88
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 12.88
Interaction Types & Directionality:
agonist (activating) binder Interaction Info:
Mechanism of Interaction Atrial natriuretic peptide receptor A agonist Direct Interaction yes Trial Name nesiritide ,Natrecor -
Interaction Score: 3.86
Interaction Types & Directionality:
agonist (activating) Interaction Info:
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Interaction Score: 3.09
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 3.09
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name MQX-503, nitroglycerin 0.9% topical cream,Vascana Novel drug target Established target
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- Version: 101_38
Alternate Names:
NPR1 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
ATRIAL NATRIURETIC PEPTIDE RECEPTOR A PRECURSOR (ANP-A) (ANPRA) (GC-A) (GUANYLATE CYCLASE) (EC 4.6.1.2) (NPR-A) (ATRIAL NATRIURETIC PEPTIDE A-TYPE RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P16066] Description NPR1 Display Id ENSG00000169418 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
NPR1 Gene Symbol Gene Info:
Target Class Receptors Target Subclass EC:4.6.1.2 Publications:
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Alternate Names:
NPR1 Gene Symbol P16066 Uniprot Accession ANPRA_HUMAN Uniprot Id Gene Info:
Target Subclass RGC Target Main Class Receptors Transmembrane Helix Count 1 Publications:
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- Version: 11-September-2012
Alternate Names:
ANPRA_HUMAN Uniprot Id ATRIAL NATRIURETIC PEPTIDE RECEPTOR 1 Uniprot Protein Name 4881 Entrez Gene Id Gene Info:
Interpro Acc IPR001245 Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: 2020.06.01
Alternate Names:
NPR1 TTD Gene Abbreviation T71230 TTD Target ID Gene Info:
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- Version: 31-May-2017
Alternate Names:
ENSG00000169418 Gene Symbol NPR1 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
ANPRA GENE_SYMBOL NPR1 GENE_SYMBOL Atrial natriuretic peptide receptor 1 UNIPROT Gene Info:
Publications:
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Alternate Names:
Atrial natriuretic peptide receptor 1 Gene Name P16066 UniProt ID Gene Info:
Gene Categories:
KINASE Publications: