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NPPC Gene Record

  • Summary
  • Interactions
  • Claims
  • NPPC 4880 Druggable Genome

    Alternate Names:

    4880
    NATRIURETIC PEPTIDE C
    NPPC
    CNP
    CNP2
    600296
    7941
    ENSG00000163273
    OTTHUMG00000133232
    C-type natriuretic peptide
    T87689

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    HORMONE ACTIVITY
    DRUGGABLE GENOME

    Publications:

    Khurana et al., 1993, Receptor-mediated stimulatory effect of atrial natriuretic factor, brain natriuretic peptide, and C-type natriuretic peptide on testosterone production in purified mouse Leydig cells: activation of cholesterol side-chain cleavage enzyme., Endocrinology
    Charles et al., 1995, Central C-type natriuretic peptide augments the hormone response to hemorrhage in conscious sheep., Peptides
    Noubani et al., 2000, B-type natriuretic peptide receptor expression and activity are hormonally regulated in rat ovarian cells., Endocrinology
    Zhang et al., Shear stress induction of C-type natriuretic peptide (CNP) in endothelial cells is independent of NO autocrine signaling., Ann Biomed Eng
    Jászberényi et al., 1998, Effects of C-type natriuretic peptide on pituitary-adrenal activation in rats., Neuroreport
    Nishimura et al., 1998, Roles of brain angiotensin II and C-type natriuretic peptide in deoxycorticosterone acetate-salt hypertension in rats., J. Hypertens.
    Yamada et al., 1996, Production of C-type natriuretic peptide in human aortic endothelial cells induced by activation of protein kinase C., Am. J. Hypertens.
  • VOSORITIDE   NPPC

    Interaction Score: 6.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • ETHER   NPPC

    Interaction Score: 2.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9721940


    Sources:
    NCI

  • ANDROSTENEDIONE   NPPC

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8404664


    Sources:
    NCI

  • VASOPRESSIN   NPPC

    Interaction Score: 0.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9794722


    Sources:
    NCI

  • STAUROSPORINE   NPPC

    Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8879350


    Sources:
    NCI

  • DIETHYLSTILBESTROL   NPPC

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10650935


    Sources:
    NCI

  • TESTOSTERONE   NPPC

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8404664


    Sources:
    NCI

  • HYDROCORTISONE   NPPC

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7716064


    Sources:
    NCI

  • PROGESTERONE   NPPC

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8404664


    Sources:
    NCI

  • DEXAMETHASONE   NPPC

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10468226


    Sources:
    NCI

  • Ensembl: ENSG00000163273

    • Version: 101_38

    Alternate Names:
    NPPC Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: NPPC

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Ueda et al., 1991, Distribution and characterization of immunoreactive porcine C-type natriuretic peptide., Biochem. Biophys. Res. Commun.
    Kim et al., 2001, C-type natriuretic peptide system in rabbit oviduct., Peptides
    Zhang et al., Shear stress induction of C-type natriuretic peptide (CNP) in endothelial cells is independent of NO autocrine signaling., Ann Biomed Eng

  • HingoraniCasas: ENSG00000163273

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000163273 Gene Symbol
    NPPC Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: NPPC

    • Version: 01-February-2022

    Alternate Names:
    CNP2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    HORMONE ACTIVITY

    Publications:

  • TTD: C-type natriuretic peptide

    • Version: 2020.06.01

    Alternate Names:
    NPPC TTD Gene Abbreviation
    T87689 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21