• Interaction Score: 3.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type anaplastic large cell lymphoma
    Response Type resistant
    Approval Status Preclinical


    Sources:
    JAX-CKB

  • Interaction Score: 2.96

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type anaplastic large cell lymphoma
    Response Type resistant
    Approval Status Preclinical

  • Interaction Score: 2.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type acute myeloid leukemia
    Response Type predicted – sensitive
    Approval Status Clinical Study

    PMIDs:
    26634271


    Sources:
    JAX-CKB

  • Interaction Score: 1.78

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type anaplastic large cell lymphoma
    Response Type decreased response
    Approval Status Preclinical


    Sources:
    JAX-CKB

  • Interaction Score: 1.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type acute myeloid leukemia
    Response Type sensitive
    Approval Status Preclinical


    Sources:
    JAX-CKB

  • Interaction Score: 1.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type anaplastic large cell lymphoma
    Response Type resistant
    Approval Status Preclinical


    Sources:
    JAX-CKB

  • Interaction Score: 1.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type anaplastic large cell lymphoma
    Response Type resistant
    Approval Status Preclinical

  • Interaction Score: 1.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type Advanced Solid Tumor
    Response Type resistant
    Approval Status Preclinical

    PMIDs:
    25749034


    Sources:
    JAX-CKB

  • Interaction Score: 0.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    FDA PharmGKB

  • Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type acute myeloid leukemia
    Response Type sensitive
    Approval Status Phase I

    PMIDs:
    27406088


    Sources:
    JAX-CKB

  • Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    FDA PharmGKB

  • Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:


    Sources:
    CIViC

  • Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Response Type sensitive
    combination therapy Ixazomib + Vorinostat
    Indication/Tumor Type acute myeloid leukemia

    PMIDs:
    26634271


    Sources:
    JAX-CKB

  • Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type anaplastic large cell lymphoma
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    26939704


    Sources:
    JAX-CKB

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    ligand

    Interaction Info:

    PMIDs:
    26340163


    Sources:
    DrugBank

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family Chemotherapy
    Alteration NPM1:.

    PMIDs:
    None found


    Sources:
    CGI