DGIdb - NME1 Gene Record

NME1 4830

Alternate Names:

4830
NME/NM23 NUCLEOSIDE DIPHOSPHATE KINASE 1
NME1
AWD
GAAD
NB
NBS
NDKA
NDPK-A
NDPKA
NM23
NM23-H1
156490
7849
ENSG00000239672
OTTHUMG00000137474
BE0003106
P15531
PA249
Nucleoside diphosphate kinase A

Gene Info:

Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

KINASE

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics
Huang et al., 2005, Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells., J. Nutr.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
She YM et al., 2003, Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry., Mol Cell Proteomics
Smith SD et al., 2004, Using immobilized metal affinity chromatography, two-dimensional electrophoresis and mass spectrometry to identify hepatocellular proteins with copper-binding ability., J Proteome Res
Buczynski G et al., 1990, Nucleoside diphosphate kinase from Xenopus oocytes; partial purification and characterization., Biochim Biophys Acta

DEOXYGUANOSINE TRIPHOSPHATE NME1

Interaction Score: 15.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
ADENOSINE PHOSPHONOACETIC ACID NME1

Interaction Score: 15.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
STAVUDINE TRIPHOSPHATE NME1

Interaction Score: 15.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL259724 NME1

Interaction Score: 15.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL1232205 NME1

Interaction Score: 15.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL405730 NME1

Interaction Score: 15.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
SELENOCYSTEINE NME1

Interaction Score: 7.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
LYCOPENE NME1

Interaction Score: 0.95

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16140886

Sources:
NCI
CHEMBL384759 NME1

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
TENOFOVIR NME1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ZIDOVUDINE NME1

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22960662

Sources:
PharmGKB
LAMIVUDINE NME1

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
ZINC CHLORIDE NME1

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
14534351 2176546

Sources:
DrugBank
COPPER NME1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351 15359738

Sources:
DrugBank
METHYLDOPA NME1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank

Ensembl: ENSG00000239672
- Version: 101_38
Alternate Names:

NME1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
PharmGKB: NME1
- Version: 18-August-2020
Alternate Names:

PA249 PharmGKB ID

Gene Info:

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

DrugBank: BE0003106

Version: 5.1.7

Alternate Names:

NME1 DrugBank Gene Name

P15531 UniProt Accession

4830 Entrez Gene Id

Gene Info:

Publications:

She YM et al., 2003, Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry., Mol Cell Proteomics

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

NCI: NME1
- Version: 14-September-2017
Alternate Names:

Gene Info:

Publications:

Huang et al., 2005, Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells., J. Nutr.
Pharos: NME1
- Version: 03-September-2020
Alternate Names:

Nucleoside diphosphate kinase A Gene Name

P15531 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:

NME1	DrugBank Gene Name
P15531	UniProt Accession
4830	Entrez Gene Id

NME1 Gene Record

NME1 4830

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16140886

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22960662

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 14534351 2176546

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14534351 15359738

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14534351

Sources: DrugBank

Ensembl: ENSG00000239672

Alternate Names: NME1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: NME1

Alternate Names: PA249 PharmGKB ID

Gene Info:

Publications: Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

DrugBank: BE0003106

Alternate Names: NME1 DrugBank Gene Name P15531 UniProt Accession 4830 Entrez Gene Id

Gene Info:

NCI: NME1

Alternate Names:

Gene Info:

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
16140886

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
22960662

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
14534351 2176546

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
14534351 15359738

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
14534351

Sources:
DrugBank

Alternate Names:

NME1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PA249 PharmGKB ID

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

Alternate Names:

NME1 DrugBank Gene Name

P15531 UniProt Accession

4830 Entrez Gene Id

Publications:

Huang et al., 2005, Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells., J. Nutr.

Alternate Names:

Nucleoside diphosphate kinase A Gene Name

P15531 UniProt ID

Gene Categories:

KINASE