DGIdb - NEDD4L Gene Record

NEDD4L 23327

Alternate Names:

23327
NEURAL PRECURSOR CELL EXPRESSED, DEVELOPMENTALLY DOWN-REGULATED 4-LIKE, E3 UBIQUITIN PROTEIN LIGASE
NEDD4L
NEDD4-2
NEDD4.2
PVNH7
RSP5
hNEDD4-2
606384
7728
ENSG00000049759
OTTHUMG00000179875
Q96PU5
KIAA0439
PA31534
NEDD4 LIKE E3 UBIQUITIN PROTEIN LIGASE
E3 ubiquitin-protein ligase NEDD4-like

Gene Info:

Gene Biotype	PROTEIN_CODING

(0 More Sources)

Gene Categories: Category Details

ENZYME

Publications:

Antypa N et al., 2014, Genomewide interaction and enrichment analysis on antidepressant response., Psychol Med
Svensson-Färbom P et al., 2011, A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients., J Hypertens
Luo F et al., 2009, A functional variant of NEDD4L is associated with hypertension, antihypertensive response, and orthostatic hypotension., Hypertension
Manunta P et al., 2008, Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodium-related blood pressure regulation., Hypertension

HYDROCHLOROTHIAZIDE NEDD4L

Interaction Score: 3.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21052022 19635985 18591455

Sources:
PharmGKB
CITALOPRAM NEDD4L

Interaction Score: 1.87

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23809733

Sources:
PharmGKB

Ensembl: ENSG00000049759
- Version: 101_38
Alternate Names:

NEDD4L Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: NEDD4L

Version: 18-August-2020

Alternate Names:

PA31534 PharmGKB ID

Gene Info:

Publications:

Manunta P et al., 2008, Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodium-related blood pressure regulation., Hypertension

Svensson-Färbom P et al., 2011, A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients., J Hypertens

Antypa N et al., 2014, Genomewide interaction and enrichment analysis on antidepressant response., Psychol Med

HumanProteinAtlas: NEDD4L
- Version: 19.3
Alternate Names:

ENSG00000049759 Ensembl Gene ID

KIAA0439 Human Protein Atlas Gene Synonym

NEDD4-2 Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories:

ENZYME

Publications:
Pharos: NEDD4L
- Version: 01-February-2022
Alternate Names:

E3 ubiquitin-protein ligase NEDD4-like Gene Name

Q96PU5 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications: