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NEDD4L Gene Record

  • Summary
  • Interactions
  • Claims
  • NEDD4L 23327

    Alternate Names:

    23327
    NEURAL PRECURSOR CELL EXPRESSED, DEVELOPMENTALLY DOWN-REGULATED 4-LIKE, E3 UBIQUITIN PROTEIN LIGASE
    NEDD4L
    NEDD4-2
    NEDD4.2
    PVNH7
    RSP5
    hNEDD4-2
    606384
    7728
    ENSG00000049759
    OTTHUMG00000179875
    Q96PU5
    KIAA0439
    PA31534
    E3 ubiquitin-protein ligase NEDD4-like

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Antypa N et al., 2014, Genomewide interaction and enrichment analysis on antidepressant response., Psychol Med
    Manunta P et al., 2008, Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodium-related blood pressure regulation., Hypertension
    Svensson-Färbom P et al., 2011, A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients., J Hypertens
    Luo F et al., 2009, A functional variant of NEDD4L is associated with hypertension, antihypertensive response, and orthostatic hypotension., Hypertension
  • HYDROCHLOROTHIAZIDE   NEDD4L

    Interaction Score: 3.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18591455 21052022 19635985


    Sources:
    PharmGKB

  • CITALOPRAM   NEDD4L

    Interaction Score: 1.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23809733


    Sources:
    PharmGKB

  • Ensembl: ENSG00000049759

    • Version: 101_38

    Alternate Names:
    NEDD4L Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: NEDD4L

    • Version: 18-August-2020

    Alternate Names:
    PA31534 PharmGKB ID

    Gene Info:

    Publications:
    Manunta P et al., 2008, Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodium-related blood pressure regulation., Hypertension
    Svensson-Färbom P et al., 2011, A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients., J Hypertens
    Antypa N et al., 2014, Genomewide interaction and enrichment analysis on antidepressant response., Psychol Med

  • HumanProteinAtlas: NEDD4L

    • Version: 19.3

    Alternate Names:
    ENSG00000049759 Ensembl Gene ID
    KIAA0439 Human Protein Atlas Gene Synonym
    NEDD4-2 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • Pharos: NEDD4L

    • Version: 03-September-2020

    Alternate Names:
    E3 ubiquitin-protein ligase NEDD4-like Gene Name
    Q96PU5 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21