• MMP12 4321 Druggable Genome

    Alternate Names:

    4321
    MATRIX METALLOPEPTIDASE 12
    MMP12
    HME
    ME
    MME
    MMP-12
    601046
    7158
    ENSG00000262406
    OTTHUMG00000165848
    P39900
    MATRIX METALLOPROTEINASE-12
    MACROPHAGE METALLOELASTASE
    MMP12_HUMAN
    ENSG00000110347
    MACROPHAGE METALLOELASTASE PRECURSOR (EC 3.4.24.65) (HME) (MATRIX METALLOPROTEINASE-12) (MMP-12) (MACROPHAGE ELASTASE) (ME). [SOURCE:UNIPROT/SWISSPROT;ACC:P39900]
    1636
    NP_002417
    NM_002426
    T03500

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name M10: Matrix metallopeptidase
    GuideToPharmacology Gene Category ID 738
    Human Readable Name PROTEASE
    Interpro Name Peptidase, metallopeptidase
    Uniprot Status Swiss-Prot
    Interpro Acc IPR006026
    Interpro Short Name Peptidase_Metallo
    Interpro Type Domain
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 5.32

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? True
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


  • Interaction Score: 2.66

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24074025


    Sources:
    DTC

  • Interaction Score: 1.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24074025


    Sources:
    DTC

  • Interaction Score: 1.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24074025


    Sources:
    DTC

  • Interaction Score: 1.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24074025


    Sources:
    DTC

  • Interaction Score: 0.82

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    MMP12 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000110347 Ensembl Gene Id
    MACROPHAGE METALLOELASTASE PRECURSOR (EC 3.4.24.65) (HME) (MATRIX METALLOPROTEINASE-12) (MMP-12) (MACROPHAGE ELASTASE) (ME). [SOURCE:UNIPROT/SWISSPROT;ACC:P39900] Description
    MMP12 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    MMP12 Uniprot Gene Name
    4321 Entrez Gene Id
    MMP12_HUMAN Uniprot Id

    Gene Info:
    Human Readable Name PROTEASE
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Peptidase, metallopeptidase

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    7158 HUGO Gene ID
    7158 HUGO Gene Symbol
    matrix metallopeptidase 12 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name M10: Matrix metallopeptidase
    GuideToPharmacology Gene Category ID 738

    Gene Categories:
    ENZYME

    Publications:

    • Version: 02-September-2020
    • Version: 27-Jun-2013

    Alternate Names:
    4321 Gene ID
    HME dGene Synonym
    ME dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    MMP-12 TTD Gene Abbreviation
    T03500 TTD Target ID

    Gene Info:

    Publications: