DGIdb - MGLL Gene Record

MGLL 11343 Druggable Genome

Alternate Names:

11343
MONOGLYCERIDE LIPASE
MGLL
HU-K5
HUK5
MAGL
MGL
609699
17038
ENSG00000074416
OTTHUMG00000159641
Q99685
1399
Monoacylglycerol lipase
T18664
NM_007283
NP_009214

Gene Info:

Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	2-Acylglycerol ester turnover
GuideToPharmacology Gene Category ID	944
GuideToPharmacology Gene Category Name	Hydrolases
GuideToPharmacology Gene Category ID	799
GuideToPharmacology Gene Category Name	S33: Prolyl aminopeptidase
GuideToPharmacology Gene Category ID	917

(1 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
ENZYME

Publications:

Matuszak N et al., 2009, Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors., J Med Chem
Minkkilä A et al., 2009, The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors., Eur J Med Chem
Matuszak N et al., 2011, Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone., Bioorg Med Chem Lett

OCTHILINONE MGLL

Interaction Score: 28.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22056744

Sources:
DTC
CHEMBL565711 MGLL

Interaction Score: 28.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19583260

Sources:
DTC
CHEMBL76012 MGLL

Interaction Score: 14.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19583260

Sources:
DTC
URB-597 MGLL

Interaction Score: 7.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19232787

Sources:
DTC

Ensembl: ENSG00000074416
- Version: 101_38
Alternate Names:

MGLL Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
GuideToPharmacology: 11343
- Version: 29-September-2020
Alternate Names:

17038 HUGO Gene ID

17038 HUGO Gene Symbol

monoglyceride lipase HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name 2-Acylglycerol ester turnover

GuideToPharmacology Gene Category ID 944

GuideToPharmacology Gene Category Name Hydrolases

Gene Categories:

ENZYME

Publications:

DTC: MGLL

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Minkkilä A et al., 2009, The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors., Eur J Med Chem

Matuszak N et al., 2011, Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone., Bioorg Med Chem Lett

Matuszak N et al., 2009, Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors., J Med Chem

HingoraniCasas: ENSG00000074416
- Version: 31-May-2017
Alternate Names:

ENSG00000074416 Gene Symbol

MGLL Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
TTD: Monoglyceride lipase
- Version: 2020.06.01
Alternate Names:

MAGL TTD Gene Abbreviation

T18664 TTD Target ID

Gene Info:

Publications:

17038	HUGO Gene ID
17038	HUGO Gene Symbol
monoglyceride lipase	HUGO Gene Name

MAGL	TTD Gene Abbreviation
T18664	TTD Target ID

MGLL Gene Record

MGLL 11343 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

OCTHILINONE MGLL

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22056744

Sources: DTC

CHEMBL565711 MGLL

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19583260

Sources: DTC

CHEMBL76012 MGLL

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19583260

Sources: DTC

URB-597 MGLL

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19232787

Sources: DTC

Ensembl: ENSG00000074416

Alternate Names: MGLL Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

GuideToPharmacology: 11343

Alternate Names: 17038 HUGO Gene ID 17038 HUGO Gene Symbol monoglyceride lipase HUGO Gene Name

Gene Info: GuideToPharmacology Gene Category Name 2-Acylglycerol ester turnover GuideToPharmacology Gene Category ID 944 GuideToPharmacology Gene Category Name Hydrolases

Gene Categories: ENZYME

Publications:

DTC: MGLL

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000074416

Alternate Names: ENSG00000074416 Gene Symbol MGLL Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

TTD: Monoglyceride lipase

Alternate Names: MAGL TTD Gene Abbreviation T18664 TTD Target ID

Gene Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
22056744

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19583260

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19583260

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19232787

Sources:
DTC

Alternate Names:

MGLL Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

17038 HUGO Gene ID

17038 HUGO Gene Symbol

monoglyceride lipase HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name 2-Acylglycerol ester turnover

GuideToPharmacology Gene Category ID 944

GuideToPharmacology Gene Category Name Hydrolases

Gene Categories:

ENZYME

Alternate Names:

ENSG00000074416 Gene Symbol

MGLL Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

MAGL TTD Gene Abbreviation

T18664 TTD Target ID