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METAP2 10988 Druggable Genome
Alternate Names:
10988 METHIONYL AMINOPEPTIDASE 2 METAP2 MAP2 MNPEP p67eIF2 601870 16672 ENSG00000111142 OTTHUMG00000170280 Methionine aminopeptidase 2 MetAP 2 p67 MAP 2 Peptidase M Initiation factor 2-associated 67 kDa glycoprotein P50579 1573 NM_006838 NP_006829 BE0001534 AMPM2_HUMAN METHIONINE AMINOPEPTIDASE 2 (EC 3.4.11.18) (METAP 2) (PEPTIDASE M 2) (INITIATION FACTOR 2 ASSOCIATED 67 KDA GLYCOPROTEIN) (P67) (P67EIF2). [SOURCE:UNIPROT/SWISSPROT;ACC:P50579] T75596 Gene Info:
Target Class Enzymes Target Subclass EC:3.4.11.18 GuideToPharmacology Gene Category Name M24: Methionyl aminopeptidase GuideToPharmacology Gene Category ID 746 Human Readable Name PROTEASE Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Interpro Type Domain Interpro Name Peptidase M24, structural domain Uniprot Status Swiss-Prot Interpro Acc IPR000994 Interpro Short Name Pept_M24_structural-domain Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE PROTEASE DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 14.2
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name ZGN-433 Novel drug target Novel Target Specific Action of the Ligand Inhibition -
Interaction Types & Directionality:
n/a Interaction Info:
Novel drug target Novel Target Trial Name PPI-2458 -
Interaction Score: 7.1
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Interaction Score: 7.1
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Interaction Score: 7.1
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Interaction Score: 7.1
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Interaction Score: 7.1
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Interaction Score: 7.1
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Interaction Score: 3.55
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Interaction Score: 2.66
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Interaction Score: 2.13
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Interaction Score: 1.78
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Interaction Score: 0.51
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Interaction Score: 0.18
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Aminopeptidases inhibitor Direct Interaction yes
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- Version: 101_38
Alternate Names:
METAP2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
METAP2 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:3.4.11.18 Publications:
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- Version: 11-September-2012
Alternate Names:
AMPM2_HUMAN Uniprot Id 10988 Entrez Gene Id METAP2 Uniprot Gene Name Gene Info:
Human Readable Name PROTEASE Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Gene Categories:
PROTEASE, DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000111142 Ensembl Gene Id METAP2 Display Id METHIONINE AMINOPEPTIDASE 2 (EC 3.4.11.18) (METAP 2) (PEPTIDASE M 2) (INITIATION FACTOR 2 ASSOCIATED 67 KDA GLYCOPROTEIN) (P67) (P67EIF2). [SOURCE:UNIPROT/SWISSPROT;ACC:P50579] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
16672 HUGO Gene ID 16672 HUGO Gene Symbol methionyl aminopeptidase 2 HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name M24: Methionyl aminopeptidase GuideToPharmacology Gene Category ID 746 Gene Categories:
ENZYME Publications:
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Alternate Names:
METAP2 DrugBank Gene Name P50579 UniProt Accession 10988 Entrez Gene Id Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000111142 Gene Symbol METAP2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
P67EIF2 GENE_SYMBOL METAP2 GENE_SYMBOL Methionine aminopeptidase 2 UNIPROT Gene Info:
Publications:
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Alternate Names:
Methionine aminopeptidase 2 Gene Name P50579 UniProt ID Gene Info:
Gene Categories:
KINASE Publications:
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Alternate Names:
10988 Gene ID MAP2 dGene Synonym MNPEP dGene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
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- Version: 2020.06.01
Alternate Names:
METAP2 TTD Gene Abbreviation T75596 TTD Target ID Gene Info:
Publications: