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ME3 Gene Record

  • Summary
  • Interactions
  • Claims
  • ME3 10873

    Alternate Names:

    10873
    MALIC ENZYME 3
    ME3
    NADP-ME
    604626
    6985
    ENSG00000151376
    OTTHUMG00000167217
    Q16798
    NADP-dependent malic enzyme, mitochondrial

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Gupta et al., 1991, Androgen-estrogen synergy in the regulation of energy metabolism in epididymis and vas deferens of rhesus monkey., Endocr. Res.
    Heath et al., 1996, Glycation-induced inactivation of malate dehydrogenase protection by aspirin and a lens molecular chaperone, alpha-crystallin., Biochim. Biophys. Acta
    Su KL et al., 2009, Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme., Bioorg Med Chem
  • GLUTACONATE   ME3

    Interaction Score: 24.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19595601


    Sources:
    DTC

  • MALONIC ACID   ME3

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19595601


    Sources:
    DTC

  • MALEIC ACID   ME3

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19595601


    Sources:
    DTC

  • ANDROSTANOLONE   ME3

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1811987


    Sources:
    NCI

  • ASPIRIN   ME3

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8611656


    Sources:
    NCI

  • Ensembl: ENSG00000151376

    • Version: 101_38

    Alternate Names:
    ME3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: ME3

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Gupta et al., 1991, Androgen-estrogen synergy in the regulation of energy metabolism in epididymis and vas deferens of rhesus monkey., Endocr. Res.
    Heath et al., 1996, Glycation-induced inactivation of malate dehydrogenase protection by aspirin and a lens molecular chaperone, alpha-crystallin., Biochim. Biophys. Acta

  • DTC: ME3

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Su KL et al., 2009, Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme., Bioorg Med Chem

  • Pharos: ME3

    • Version: 01-February-2022

    Alternate Names:
    NADP-dependent malic enzyme, mitochondrial Gene Name
    Q16798 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21