• MAP3K9 4293 Druggable Genome

    Alternate Names:

    4293
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9
    MAP3K9
    MEKK9
    MLK1
    PRKE1
    600136
    6861
    ENSG00000006432
    OTTHUMG00000171249
    P80192
    M3K9_HUMAN
    Mixed lineage kinase 1
    2084
    NP_149132
    NM_033141
    BE0004386
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 (EC 2.7.1.37) (MIXED LINEAGE KINASE 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P80192]
    T19760

    Gene Info:

    Uniprot Status Swiss-Prot
    Interpro Acc IPR001245
    Interpro Type Domain
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name KINASE
    GuideToPharmacology Gene Category Name MLK subfamily
    GuideToPharmacology Gene Category ID 524
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
    TRANSCRIPTION FACTOR
  • Interaction Score: 3.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 2.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    PMIDs:
    None found


  • Interaction Score: 1.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.47

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

    • Version: 101_38

    Alternate Names:
    MAP3K9 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    MAP3K9 Display Id
    ENSG00000006432 Ensembl Gene Id
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 (EC 2.7.1.37) (MIXED LINEAGE KINASE 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P80192] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    4293 Entrez Gene Id
    MAP3K9 Uniprot Gene Name
    ENSG00000006432 Ensembl Gene Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Acc IPR001245
    Interpro Type Domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6861 HUGO Gene ID
    6861 HUGO Gene Symbol
    mitogen-activated protein kinase kinase kinase 9 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name MLK subfamily
    GuideToPharmacology Gene Category ID 524

    Gene Categories:
    ENZYME

    Publications:

    • Version: 5.1.7
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000006432 Gene Symbol
    MAP3K9 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PRKE1 GENE_SYMBOL
    MAP3K9 GENE_SYMBOL
    Mitogen-activated protein kinase kinase kinase 9 UNIPROT

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000006432 Ensembl Gene ID
    MEKK9 Human Protein Atlas Gene Synonym
    MLK1 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Mitogen-activated protein kinase kinase kinase 9 Gene Name
    P80192 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    MLK1 GO Gene Synonym
    PRKE1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    4293 Gene ID
    MEKK9 dGene Synonym
    MLK1 dGene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    MAP3K9 TTD Gene Abbreviation
    T19760 TTD Target ID

    Gene Info:

    Publications: