• MAP3K13 9175 Druggable GenomeClinically Actionable

    Alternate Names:

    9175
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13
    MAP3K13
    LZK
    MEKK13
    MLK
    604915
    6852
    ENSG00000073803
    OTTHUMG00000156673
    Leucine zipper-bearing kinase
    Mixed lineage kinase
    2073
    O43283
    NP_004712
    NM_001242314
    M3K13_HUMAN
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 (EC 2.7.1.37) (MIXED LINEAGE KINASE) (MLK) (LEUCINE ZIPPER-BEARING KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:O43283]

    Gene Info:

    GuideToPharmacology Gene Category Name LZK subfamily
    GuideToPharmacology Gene Category ID 523
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Human Readable Name KINASE
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Acc IPR001245
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

  • Interaction Score: 7.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Mitogen-activated protein kinase kinase kinase 13 inhibitor

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    MAP3K13 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000073803 Ensembl Gene Id
    MAP3K13 Display Id
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 (EC 2.7.1.37) (MIXED LINEAGE KINASE) (MLK) (LEUCINE ZIPPER-BEARING KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:O43283] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000073803 Ensembl Gene Id
    O43283 Uniprot Accession
    9175 Entrez Gene Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6852 HUGO Gene ID
    6852 HUGO Gene Symbol
    mitogen-activated protein kinase kinase kinase 13 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name LZK subfamily
    GuideToPharmacology Gene Category ID 523

    Gene Categories:
    ENZYME

    Publications:

    • Version: chembl_23

    Alternate Names:
    LZK GENE_SYMBOL
    MAP3K13 GENE_SYMBOL
    Mitogen-activated protein kinase kinase kinase 13 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000073803 Gene Symbol
    MAP3K13 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    9175 Gene ID
    LZK dGene Synonym
    MEKK13 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    LZK GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Mitogen-activated protein kinase kinase kinase 13 Gene Name
    O43283 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: