• MAP3K10 4294 Druggable Genome

    Alternate Names:

    4294
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 10
    MAP3K10
    MEKK10
    MLK2
    MST
    600137
    6849
    ENSG00000130758
    OTTHUMG00000182591
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 10 (EC 2.7.1.37) (MIXED LINEAGE KINASE 2) (PROTEIN KINASE MST). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02779]
    Q02779
    M3K10_HUMAN
    Mixed lineage kinase 2
    Protein kinase MST
    2070
    NP_002437
    NM_002446
    BE0009462

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Acc IPR001245
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Uniprot Evidence 1: Evidence at protein level
    GuideToPharmacology Gene Category Name MLK subfamily
    GuideToPharmacology Gene Category ID 524
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 1.62

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

    • Version: 101_38

    Alternate Names:
    MAP3K10 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000130758 Ensembl Gene Id
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 10 (EC 2.7.1.37) (MIXED LINEAGE KINASE 2) (PROTEIN KINASE MST). [SOURCE:UNIPROT/SWISSPROT;ACC:Q02779] Description
    MAP3K10 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    4294 Entrez Gene Id
    ENSG00000130758 Ensembl Gene Id
    Q02779 Uniprot Accession

    Gene Info:
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6849 HUGO Gene ID
    6849 HUGO Gene Symbol
    mitogen-activated protein kinase kinase kinase 10 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name MLK subfamily
    GuideToPharmacology Gene Category ID 524

    Gene Categories:
    ENZYME

    Publications:

    • Version: 5.1.7

    Alternate Names:
    MAP3K10 DrugBank Gene Name
    Q02779 UniProt Accession
    4294 Entrez Gene Id

    Gene Info:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000130758 Gene Symbol
    MAP3K10 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    MST GENE_SYMBOL
    MAP3K10 GENE_SYMBOL
    Mitogen-activated protein kinase kinase kinase 10 UNIPROT

    Gene Info:

    Publications:

    • Version: 15-July-2019

    Alternate Names:
    MAP3K10 Gene Symbol

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Mitogen-activated protein kinase kinase kinase 10 Gene Name
    Q02779 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    MLK2 GO Gene Synonym
    MST GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    4294 Gene ID
    MEKK10 dGene Synonym
    MLK2 dGene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, KINASE

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: