4067 |
LYN PROTO-ONCOGENE, SRC FAMILY TYROSINE KINASE |
LYN |
JTK8 |
p53Lyn |
p56Lyn |
165120 |
6735 |
ENSG00000254087 |
OTTHUMG00000044345 |
V-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
Tyrosine-protein kinase Lyn |
Lck/Yes-related novel protein tyrosine kinase |
P07948 |
LYN_HUMAN |
ENSG00000147507 |
TYROSINE-PROTEIN KINASE LYN (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P07948] |
T68163 |
3359 |
Target Class | Enzymes |
Target Subclass | EC:2.7.10.2 |
Human Readable Name | DRUGGABLE GENOME |
Initial Gene Query | LYN |
Counted Citations from 1950-2000 | 1494 |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Interpro Name | Serine-threonine/tyrosine-protein kinase catalytic domain |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Type | Domain |
Interpro Acc | IPR001245 |
Human Readable Name | KINASE |
Uniprot Status | Swiss-Prot |
Gene Biotype | PROTEIN_CODING |
KINASE |
TYROSINE KINASE |
DRUG RESISTANCE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
ENZYME |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase Lyn inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase Lyn inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase Lyn inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Trial Name | masitinib, AB1010 |
Novel drug target | Novel Target |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | SRC inhibitor |
Direct Interaction | yes |
LYN | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
LYN | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.10.2 |
4067 | Entrez Gene ID |
Initial Gene Query | LYN |
Counted Citations from 1950-2000 | 1494 |
KINASE |
P07948 | Uniprot Accession |
LYN_HUMAN | Uniprot Id |
ENSG00000254087 | Ensembl Gene Id |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Interpro Name | Serine-threonine/tyrosine-protein kinase catalytic domain |
Human Readable Name | DRUGGABLE GENOME |
KINASE, DRUGGABLE GENOME |
LYN | Display Id |
TYROSINE-PROTEIN KINASE LYN (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:P07948] | Description |
ENSG00000147507 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
4067 | Entrez Gene ID |
3359 | CIViC Gene ID |
DRUG RESISTANCE |
LYN | Gene Symbol |
JTK8 | GENE_SYMBOL |
LYN | GENE_SYMBOL |
Tyrosine-protein kinase Lyn | UNIPROT |
4067 | Entrez Gene Id |
LYN | MyCancerGenome Gene Symbol |
LYN | MyCancerGenome Reported Gene Name |
ENSG00000254087 | Gene Symbol |
LYN | Ensembl Id |
DRUGGABLE GENOME |
ENSG00000254087 | Ensembl Gene ID |
JTK8 | Human Protein Atlas Gene Synonym |
LYN proto-oncogene, Src family tyrosine kinase | Human Protein Atlas Gene Description |
ENZYME |
JTK8 | GO Gene Synonym |
KINASE, TYROSINE KINASE |
LYN | Gene Symbol |
CLINICALLY ACTIONABLE |
4067 | Gene ID |
JTK8 | dGene Synonym |
p53Lyn | dGene Synonym |
KINASE, TYROSINE KINASE |
JTK8 | TTD Gene Abbreviation |
T68163 | TTD Target ID |
Tyrosine-protein kinase Lyn | Gene Name |
P07948 | UniProt ID |
KINASE |
CLINICALLY ACTIONABLE |