DGIdb - LTF Gene Record

LTF 4057 Druggable Genome

Alternate Names:

4057
LACTOTRANSFERRIN
LTF
GIG12
HEL110
HLF2
LF
150210
6720
ENSG00000012223
OTTHUMG00000156325
BE0000994
P02788
T67801

Gene Info:

Gene Biotype	PROTEIN_CODING

(4 More Sources)

Gene Categories: Category Details

CELL SURFACE
PROTEASE
DRUGGABLE GENOME
TRANSCRIPTION FACTOR

Publications:

Humphrey et al., 2002, Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks., J. Nutr.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Mutafchiev, 1987, [Effect of reserpine on the lactose, iron and lactoferrin content of the milk of lactating rabbits]., Eksp Med Morfol
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

CHEMBL92636 LTF

Interaction Score: 22.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL609880 LTF

Interaction Score: 22.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
PARECOXIB LTF

Interaction Score: 8.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
TTD DrugBank
NITRILOTRIACETIC ACID LTF

Interaction Score: 7.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL1230004 LTF

Interaction Score: 5.68

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
TALACTOFERRIN ALFA LTF

Interaction Score: 5.68

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
BACITRACIN LTF

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12042436

Sources:
NCI
DODECANOATE LTF

Interaction Score: 0.95

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
NIMESULIDE LTF

Interaction Score: 0.76

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
RESERPINE LTF

Interaction Score: 0.44

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3608900

Sources:
NCI

Ensembl: ENSG00000012223
- Version: 101_38
Alternate Names:

LTF Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0000994

Version: 5.1.7

Alternate Names:

LTF DrugBank Gene Name

P02788 UniProt Accession

4057 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: LTF

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Mutafchiev, 1987, [Effect of reserpine on the lactose, iron and lactoferrin content of the milk of lactating rabbits]., Eksp Med Morfol

Humphrey et al., 2002, Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks., J. Nutr.

HingoraniCasas: ENSG00000012223
- Version: 31-May-2017
Alternate Names:

ENSG00000012223 Gene Symbol

LTF Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: LTF
- Version: 03-September-2020
Alternate Names:

Lactotransferrin Gene Name

P02788 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications:
GO: LTF
- Version: 05-September-2020
Alternate Names:

GIG12 GO Gene Synonym

LF GO Gene Synonym

Gene Info:

Gene Categories:

CELL SURFACE

Publications:
dGene: LTF
- Version: 27-Jun-2013
Alternate Names:

4057 Gene ID

GIG12 dGene Synonym

HLF2 dGene Synonym

Gene Info:

Gene Categories:

PROTEASE

Publications:
TTD: Lactotransferrin
- Version: 2020.06.01
Alternate Names:

LTF TTD Gene Abbreviation

T67801 TTD Target ID

Gene Info:

Publications:

LTF	DrugBank Gene Name
P02788	UniProt Accession
4057	Entrez Gene Id

LTF Gene Record

LTF 4057 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: TTD DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12042436

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3608900

Sources: NCI

Ensembl: ENSG00000012223

Alternate Names: LTF Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0000994

Alternate Names: LTF DrugBank Gene Name P02788 UniProt Accession 4057 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: LTF

Alternate Names:

Gene Info:

Publications: Mutafchiev, 1987, [Effect of reserpine on the lactose, iron and lactoferrin content of the milk of lactating rabbits]., Eksp Med Morfol Humphrey et al., 2002, Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks., J. Nutr.

HingoraniCasas: ENSG00000012223

Alternate Names: ENSG00000012223 Gene Symbol LTF Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

Pharos: LTF

Alternate Names: Lactotransferrin Gene Name P02788 UniProt ID

Gene Info:

Gene Categories: TRANSCRIPTION FACTOR

Publications:

GO: LTF

Alternate Names: GIG12 GO Gene Synonym LF GO Gene Synonym

Gene Info:

Gene Categories: CELL SURFACE

Publications:

dGene: LTF

Alternate Names: 4057 Gene ID GIG12 dGene Synonym HLF2 dGene Synonym

Gene Info:

Gene Categories: PROTEASE

Publications:

TTD: Lactotransferrin

Alternate Names: LTF TTD Gene Abbreviation T67801 TTD Target ID

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
TTD DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
12042436

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
3608900

Sources:
NCI

Alternate Names:

LTF Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

LTF DrugBank Gene Name

P02788 UniProt Accession

4057 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Publications:

Mutafchiev, 1987, [Effect of reserpine on the lactose, iron and lactoferrin content of the milk of lactating rabbits]., Eksp Med Morfol

Humphrey et al., 2002, Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks., J. Nutr.

Alternate Names:

ENSG00000012223 Gene Symbol

LTF Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

Lactotransferrin Gene Name

P02788 UniProt ID

Gene Categories:

TRANSCRIPTION FACTOR

Alternate Names:

GIG12 GO Gene Synonym

LF GO Gene Synonym

Gene Categories:

CELL SURFACE

Alternate Names:

4057 Gene ID

GIG12 dGene Synonym

HLF2 dGene Synonym

Gene Categories:

PROTEASE

Alternate Names:

LTF TTD Gene Abbreviation

T67801 TTD Target ID