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LCAT Gene Record

  • Summary
  • Interactions
  • Claims
  • LCAT 3931 Druggable Genome

    Alternate Names:

    3931
    LECITHIN-CHOLESTEROL ACYLTRANSFERASE
    LCAT
    606967
    6522
    ENSG00000213398
    OTTHUMG00000137551
    T05661
    P04180
    Phosphatidylcholine-sterol acyltransferase

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    DRUGGABLE GENOME
    ENZYME

    Publications:

    Althaf MM et al., 2015, Familial lecithin-cholesterol acyltransferase (LCAT) deficiency; a differential of proteinuria., J Nephropathol
    Soulimane-Mokhtari et al., 2008, Serum lipoprotein composition, lecithin cholesterol acyltransferase and tissue lipase activities in pregnant diabetic rats and their offspring receiving enriched n-3 PUFA diet., Gen. Physiol. Biophys.
    Nanjee et al., 1988, Lack of association between plasma lecithin: cholesterol acyltransferase concentration and plasma sex hormone concentrations in men., Clin. Chim. Acta
    Nayak et al., 1990, Serum apolipoproteins A and B, lecithin: cholesterol acyl transferase activities and urinary cholesterol levels in nephrotic syndrome patients before and during steroid treatment., Nephron
  • RECOMBINANT HUMAN LECITHIN:CHOLESTEROL ACYLTRANSFERASE   LCAT

    Interaction Score: 30.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25657982


    Sources:
    TTD

  • PREDNISOLONE   LCAT

    Interaction Score: 1.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2314540


    Sources:
    NCI

  • TESTOSTERONE   LCAT

    Interaction Score: 0.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3383436


    Sources:
    NCI

  • STREPTOZOCIN   LCAT

    Interaction Score: 0.67

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18436977


    Sources:
    NCI

  • Ensembl: ENSG00000213398

    • Version: 101_38

    Alternate Names:
    LCAT Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TTD: Lecithin-cholesterol acyltransferase

    • Version: 2020.06.01

    Alternate Names:
    LCAT TTD Gene Abbreviation
    T05661 TTD Target ID

    Gene Info:

    Publications:
    Althaf MM et al., 2015, Familial lecithin-cholesterol acyltransferase (LCAT) deficiency; a differential of proteinuria., J Nephropathol

  • NCI: LCAT

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Nayak et al., 1990, Serum apolipoproteins A and B, lecithin: cholesterol acyl transferase activities and urinary cholesterol levels in nephrotic syndrome patients before and during steroid treatment., Nephron
    Haug et al., 1986, Hypercholesterolaemia, hypotriacylglycerolaemia and increased lipoprotein lipase activity following orchidectomy in rats., Acta Endocrinol.
    Soulimane-Mokhtari et al., 2008, Serum lipoprotein composition, lecithin cholesterol acyltransferase and tissue lipase activities in pregnant diabetic rats and their offspring receiving enriched n-3 PUFA diet., Gen. Physiol. Biophys.

  • HingoraniCasas: ENSG00000213398

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000213398 Gene Symbol
    LCAT Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: LCAT

    • Version: 19.3

    Alternate Names:
    ENSG00000213398 Ensembl Gene ID
    Lecithin-cholesterol acyltransferase Human Protein Atlas Gene Description
    P04180 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • Pharos: LCAT

    • Version: 01-February-2022

    Alternate Names:
    Phosphatidylcholine-sterol acyltransferase Gene Name
    P04180 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER, ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21