• Interaction Score: 6.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 6.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22871580


    Sources:
    DTC

  • Interaction Score: 6.38

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Integrin alpha-V/beta-3 antagonist
    Notes Targets ALPHA-V/BETA-5 INTEGRIN

  • Interaction Score: 3.19

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Integrin alpha-V/beta-6 inhibitor

    PMIDs:
    None found


  • Interaction Score: 2.55

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name CNTO-95
    Novel drug target Established target
    Mechanism of Interaction Integrin alpha-V/beta-1 antagonist

    PMIDs:
    None found


  • Interaction Score: 2.55

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Integrin alpha-V/beta-1 inhibitor

    PMIDs:
    None found


  • Interaction Score: 2.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name volociximab, E10030, Eos200-4

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 1.59

    Interaction Types & Directionality:
    antibody (inhibitory)
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-3 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.06

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name GLPG0187
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial